Description |
COP9 signalosome subunit 5 |
BCL3 transcription coactivator |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Alzheimer's disease ( 30636644 24755620)
- Alzheimer's disease (late onset) ( 23565137)
- Alzheimer's disease (onset between ages 58 and 79) ( 30979435)
- Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
- Alzheimer's disease or fasting insulin levels (pleiotropy) ( 30805717)
- Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)
- Apolipoprotein A1 levels ( 32203549)
- Apolipoprotein B levels ( 32203549)
- Asthma ( 32296059)
- Body mass index ( 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x age interaction ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Eosinophil counts ( 32888494)
- Eosinophil percentage of white cells ( 32888494 27863252)
- HDL cholesterol levels ( 32203549)
- HDL cholesterol levels in current drinkers ( 30698716)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels ( 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
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Interacting Genes |
99 interacting genes:
APCS
ARFGAP1
ATM
ATRN
BCL2L14
BCL3
BRD4
BRSK2
CACNA1C
CD274
CD93
CDKN1B
CENPT
COPS2
COPS3
COPS4
COPS6
COPS7A
COPS7B
COPS8
COPS9
CUL1
CUL2
CUL3
CUL4A
CUL4B
CUL5
DDB1
DDO
ERN1
ERRFI1
ESR1
F2RL1
GFER
GFI1B
GPS1
GTPBP3
HAND2
HIF1A
HNF4A
HNF4G
HTR6
IKBKB
ITGB2
JUN
JUND
LASP1
MAP2K2
MAP3K11
MAP3K3
MAP3K7
MAP4K3
MAP4K5
MAPK14
MAPRE1
MAX
MDC1
MDM2
MEF2C
MEF2D
MIF
MSRA
MTRES1
MYG1
NCOA1
NEDD8
NFKB1
NR4A2
NR4A3
OPRM1
PEA15
PGR
PLAC8
PPARG
PPOX
PPP1CC
PRDX2
PRKD1
PTGS2
RAD1
RAD9A
RNF139
RORA
S100A7
SHANK3
SHISA5
SMAD2
SMAD4
SMAD5
SPP1
SREBF2
TOP2A
TP53
TXN
TYK2
UCHL1
VTN
WNK1
YWHAG
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36 interacting genes:
AKT1
ANKRD28
BARD1
CHUK
COPS5
CREBBP
CTBP1
CTBP2
CTNNB1
EP300
FOS
FYN
GSK3A
GSK3B
GTF2A1
GTF2B
HDAC1
HDAC3
HDAC6
JUN
KAT5
MAPK1
MAPK3
MAPRE1
N4BP2
NCOA1
NFKB1
NFKB2
PIR
RAB9A
RELA
RUVBL2
RXRA
SHC1
TBP
TRAF6
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Entrez ID |
10987 |
602 |
HPRD ID |
06888 |
00179 |
Ensembl ID |
ENSG00000121022
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ENSG00000069399
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Uniprot IDs |
A0A024R7W9
Q92905
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B7Z3N9
P20749
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PDB IDs |
4D10
4D18
4F7O
4WSN
5JOG
5JOH
5M5Q
6R6H
6R7F
6R7H
6R7I
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1K1A
1K1B
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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