MAPRE2 and RBM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, two hybrid)

		MAPRE2	RBM6
Description		microtubule associated protein RP/EB family member 2	RNA binding motif protein 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoplasmic Microtubule Focal Adhesion Microtubule Cytoskeleton Microtubule Plus-end Spindle Midzone	Nucleus
	Molecular Function	Protein Binding Microtubule Binding Protein Kinase Binding Identical Protein Binding Microtubule Plus-end Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of ARF Protein Signal Transduction Positive Regulation Of GTPase Activity Spindle Assembly Cell Division Positive Regulation Of Keratinocyte Migration Positive Regulation Of Focal Adhesion Disassembly Protein Localization To Microtubule Plus-end	MRNA Splicing, Via Spliceosome RNA Processing
Pathways
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 26252872) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Facial morphology ( 29921221) Metabolite levels ( 23823483)	Age at first birth ( 27089180 27798627) Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 32203549) Blood protein levels ( 28240269) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Depressive symptom (appetite changes) (binary trait) ( 31530331) Depressive symptoms (binary sum-score) ( 31530331) Depressive symptoms (sum-score) ( 31530331) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Extremely high intelligence ( 29520040) Gastroesophageal reflux disease ( 31527586) General cognitive ability ( 29844566) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Height ( 28552196) Household income (MTAG) ( 31844048) Immature fraction of reticulocytes ( 32888494) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Menarche (age at onset) ( 21102462) Metabolic syndrome ( 31589552) Morning person ( 30696823) Multisite chronic pain ( 33830993) Platelet distribution width ( 32888494) Refractive error ( 32231278) Regular attendance at a gym or sports club ( 29970889) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 30297969)
Interacting Genes		28 interacting genes: APC APP AURKA AURKB CASK CDK2 CDK4 CLASP2 CLIP1 CRTAC1 DDIT4L FBXO7 GAS2L2 GTSE1 KMT2E LMNA LMO2 LNX1 MAPRE3 NIF3L1 PAXIP1 RBM10 RBM6 SLAIN2 TRAF1 TRAIP TXN2 UBC	7 interacting genes: EEF1G MAPRE2 MIRLET7D MIRLET7G PRKAR2A SF3B3 TAF7
Entrez ID		10982	10180
HPRD ID		16157	06054
Ensembl ID		ENSG00000166974	ENSG00000004534
Uniprot IDs		A0A024RC33 Q15555	A8K6Q4 E9PGM9 P78332
PDB IDs
Enriched GO Terms of Interacting Partners?
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