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YWHAQ and BAD
Number of citations of the paper that reports this interaction (PubMedID
8929531
)
532
Data Source:
BioGRID
(pull down, affinity chromatography technology, affinity chromatography technology, two hybrid)
HPRD
(two hybrid, in vitro, in vivo)
YWHAQ
BAD
Description
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
BCL2 associated agonist of cell death
Image
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Focal Adhesion
Membrane
Protein-containing Complex
Synapse
Extracellular Exosome
Mitochondrion
Mitochondrial Outer Membrane
Cytosol
Molecular Function
Protein Binding
Protein C-terminus Binding
Protein Domain Specific Binding
Identical Protein Binding
Transmembrane Transporter Binding
Protein N-terminus Binding
14-3-3 Protein Binding
Protein Binding
Phospholipid Binding
Lipid Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Protein Kinase Binding
Protein Phosphatase Binding
Protein Phosphatase 2B Binding
Protein Kinase B Binding
14-3-3 Protein Binding
Biological Process
Protein Targeting
Signal Transduction
Small GTPase Mediated Signal Transduction
Substantia Nigra Development
Cellular Protein Localization
Negative Regulation Of Ion Transmembrane Transport
Negative Regulation Of Transcription, DNA-templated
Release Of Cytochrome C From Mitochondria
Glucose Catabolic Process
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Spermatogenesis
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Response To Xenobiotic Stimulus
Response To Glucose
Positive Regulation Of Autophagy
Positive Regulation Of Mitochondrial Membrane Potential
Cytokine-mediated Signaling Pathway
Cerebral Cortex Development
Positive Regulation Of Insulin Secretion
Response To Estradiol
Response To Progesterone
Positive Regulation Of Glucokinase Activity
Response To Testosterone
Response To Oleic Acid
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Response To Hydrogen Peroxide
Glucose Homeostasis
Positive Regulation Of Apoptotic Process
Response To Amino Acid
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Type B Pancreatic Cell Proliferation
Response To Ethanol
Positive Regulation Of B Cell Differentiation
Positive Regulation Of T Cell Differentiation
Positive Regulation Of Proteolysis
ADP Metabolic Process
ATP Metabolic Process
Regulation Of Mitochondrial Membrane Permeability
Pore Complex Assembly
Positive Regulation Of Epithelial Cell Proliferation
Response To Glucocorticoid
Response To Calcium Ion
Cellular Response To Chromate
Cellular Response To Mechanical Stimulus
Cellular Response To Nicotine
Cellular Response To Lipid
Cellular Response To Hypoxia
Positive Regulation Of Release Of Cytochrome C From Mitochondria
Extrinsic Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Intrinsic Apoptotic Signaling Pathway
Activation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Neuron Death
Response To Benzene
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress
Positive Regulation Of Granulosa Cell Apoptotic Process
Positive Regulation Of Type B Pancreatic Cell Development
Pathways
Activation of BAD and translocation to mitochondria
Translocation of SLC2A4 (GLUT4) to the plasma membrane
RHO GTPases activate PKNs
TP53 Regulates Metabolic Genes
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
Regulation of localization of FOXO transcription factors
Activation of BAD and translocation to mitochondria
Activation of BAD and translocation to mitochondria
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members
NRAGE signals death through JNK
AKT phosphorylates targets in the cytosol
Constitutive Signaling by AKT1 E17K in Cancer
Drugs
Phenethyl Isothiocyanate
Navitoclax
Diseases
GWAS
Heart rate variability traits (
22174390
)
Non-response to selective serotonin reuptake inhibitors and depression (
27622933
)
Crohn's disease (
28067908
)
Heel bone mineral density (
30598549
)
Platelet count (
22423221
)
Sarcoidosis (
22837380
)
Vitiligo (
27723757
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
240 interacting genes:
AARS2
ABL1
ACSL4
ADRB2
AGTR1
AHCY
AKT1S1
ANXA1
ANXA2
APC
AR
ARHGAP10
ARHGEF16
ARHGEF2
ATP5F1A
BAD
BAX
BCAP31
BCR
BRAF
CABIN1
CAPN3
CBL
CBLL1
CCDC125
CDC25A
CDC25B
CDC25C
CDC5L
CDK11B
CDK14
CDK16
CDK17
CDK18
CDKN1A
CDKN1B
CEP170
CFL1
CHAF1A
CKM
CLTC
COPS4
CSE1L
CSNK1A1
CSNK2A1
CTPS1
DAB2IP
DCPS
DDX1
DDX3X
DHX9
DISC1
DNMT1
DYNC1H1
E2F1
EFNB1
EGFR
EIF4A3
ENO1
EPB41
EPB41L1
EPB41L3
ESR1
ESR2
EXO1
FASN
FBLN1
FGR
FSCN1
FSHR
FXYD1
GAPDH
GCN1
H2BC8
H4C14
HADHA
HAT1
HAX1
HDAC4
HDAC5
HDAC7
HNRNPC
HNRNPF
HNRNPH1
HNRNPK
HSPA1A
HSPA8
HSPB1
HUS1
IARS2
ING1
IQGAP1
IRS2
ITCH
ITGB4
ITPRID2
KANK1
KCNK15
KCNK3
KCNK9
KIF1C
KIF23
KIF5B
KLC2
KLC3
KRT1
KRT9
LARP1
LARS2
LDHA
LIMA1
LMNA
LMNB1
LMO7
LYST
MAGOH
MAP3K3
MAP3K5
MARK2
MARK3
MCM3
MDM4
MED1
MEF2D
MPL
MPRIP
MRPS27
MST1R
MTNR1B
MTOR
MYCBP2
NADK
NCL
NCOA1
NCOA3
NDE1
NFATC1
NFATC2
NFATC4
NFKB1
NIF3L1
NME7
NOLC1
NUMA1
PABPN1
PAK4
PANK1
PCM1
PDCD6
PDE3A
PDE3B
PDK1
PDPK1
PDXK
PFKFB2
PFKL
PFN1
PGK1
PHLDB2
PI4KB
PIK3C2B
PIK3C3
PIK3CB
PKM
PPFIBP1
PRDX1
PRKCQ
PRKCZ
PRKD1
PRKDC
PRMT5
PSME3
PTPN3
RAF1
RAI14
RCOR3
REM1
RFC1
RGS3
RGS7
RNASE2
RPL10A
RPL15
RPL19
RPL7
RPLP0
RPLP2
RPS3
RUVBL2
SAMSN1
SH3BP2
SLC27A2
SLC8A1
SLC8A2
SLC8A3
SMAD9
SNRPE
SOCS3
SPR
SPTA1
SPTB
SRSF3
SSBP1
SSX2IP
SUMO2
TCP1
TERT
THRA
TLN1
TNF
TNFAIP3
TP53BP2
TPI1
TPR
TRAF6
TRIM25
TRIM28
TRIM42
TSC1
TSC2
TUBA1A
TUBA3C
TUBB
UBQLN4
UCP2
UCP3
ULK4
USP8
VARS1
WDR61
WDR77
WEE1
WTAP
WWC2
WWP1
YAP1
YWHAE
YWHAG
ZC3H13
ZHX2
46 interacting genes:
ACTN2
AKT1
ARAF
BBS1
BCL2
BCL2A1
BCL2L1
BCL2L10
BCL2L2
BRAF
CDKN1A
CREB3L3
EWSR1
HRK
KEAP1
KRT31
MAP2K5
MAPK8
MCL1
PAK1
PAK5
PIM1
PIM2
PIM3
PPP1CA
PPP3CA
PRDX2
PRKACA
PRKCI
RAF1
RPS6KA1
RPS6KA2
RPS6KA3
RPS6KA5
S100A10
SFN
SNCA
STEAP3
SUMO2
WASF1
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
Entrez ID
10971
572
HPRD ID
00886
04409
Ensembl ID
ENSG00000134308
ENSG00000002330
Uniprot IDs
P27348
A0A024R562
Q92934
PDB IDs
2BTP
5IQP
6BCR
6BD2
6BQT
6KZG
6KZH
1G5J
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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