STARD3 and SCGB1A1

		STARD3	SCGB1A1
Description		StAR related lipid transfer domain containing 3	secretoglobin family 1A member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Lysosomal Membrane Endosome Endoplasmic Reticulum Membrane Cytosol Integral Component Of Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site	Extracellular Space Nuclear Envelope Cytoplasm Rough Endoplasmic Reticulum Secretory Granule Extracellular Exosome
	Molecular Function	Protein Binding Cholesterol Binding Protein Homodimerization Activity Cholesterol Transfer Activity	Protein Binding Phospholipase A2 Inhibitor Activity Polychlorinated Biphenyl Binding
	Biological Process	Lipid Metabolic Process Progesterone Biosynthetic Process Mitochondrial Transport Steroid Metabolic Process Cholesterol Metabolic Process Cholesterol Transport Vesicle Tethering To Endoplasmic Reticulum Intermembrane Lipid Transfer	Negative Regulation Of Transcription By RNA Polymerase II Signal Transduction Female Pregnancy Embryo Implantation Response To Xenobiotic Stimulus Response To Ozone Response To Lipopolysaccharide Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-4 Production Negative Regulation Of Interleukin-5 Production Response To Silicon Dioxide Response To Cytokine Negative Regulation Of T Cell Proliferation Negative Regulation Of Catalytic Activity Regulation Of MRNA Stability Regulation Of Inflammatory Response Response To Glucocorticoid Response To Fibroblast Growth Factor
Pathways		Pregnenolone biosynthesis
Drugs			4,4'-BIS([H]METHYLSULFONYL)-2,2',5,5'-TETRACHLOROBIPHENYL
Diseases
GWAS		Alcohol consumption ( 31358974) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Hemoglobin levels ( 32327693) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Smoking behaviour (cigarettes smoked per day) ( 30679032) Triglyceride levels ( 30108155) Ulcerative colitis ( 20228799)	Alanine aminotransferase levels ( 33547301) Body size at age 10 ( 32376654) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Gamma glutamyl transferase levels ( 29403010) Serum CC16 levels ( 32839289) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		11 interacting genes: AQP6 CASC3 CLEC11A CREB3 DAPK1 GOPC LMNA MYO1D RNF170 SCGB1A1 SLC39A7	9 interacting genes: AQP6 CUBN FN1 LMBR1L LRP2 MARK2 STARD3 TMEM43 TRIM32
Entrez ID		10948	7356
HPRD ID		06132	01884
Ensembl ID		ENSG00000131748	ENSG00000149021
Uniprot IDs		Q14849	A0A0S2Z4R6 P11684
PDB IDs		1EM2 2I92 5I9J 6TQR 6TQU
Enriched GO Terms of Interacting Partners?
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