EHD1 and RAB11FIP2

Number of citations of the paper that reports this interaction (PubMedID 16251358)
104

Data Source:
BioGRID (two hybrid, affinity chromatography technology, pull down)

		EHD1	RAB11FIP2
Description		EH domain containing 1	RAB11 family interacting protein 2
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GO Annotations	Cellular Component	Cytoplasm Early Endosome Lipid Droplet Plasma Membrane Endosome Membrane Membrane Ciliary Pocket Membrane Endocytic Vesicle Platelet Dense Tubular Network Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Phagocytic Cup Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Calcium Ion Binding Protein Binding ATP Binding GTP Binding Small GTPase Binding Identical Protein Binding Cadherin Binding	Protein Binding Protein Kinase Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Intracellular Protein Transport Endocytosis Positive Regulation Of Cholesterol Storage Positive Regulation Of Neuron Projection Development Endosomal Transport Neuron Projection Development Endocytic Recycling Low-density Lipoprotein Particle Clearance Cholesterol Homeostasis Protein Homooligomerization Cilium Assembly Protein Localization To Cilium Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Endocytic Recycling	Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Factors involved in megakaryocyte development and platelet production	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS			Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		13 interacting genes: AP2A1 EHBP1 EHD3 HSPB1 IGF1R MICAL1 MICALL1 MUL1 OGT RAB11FIP2 RBSN RFFL SNAP29	22 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B OGT PDZD11 PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAE YWHAG
Entrez ID		10938	22841
HPRD ID		09325	10548
Ensembl ID		ENSG00000110047	ENSG00000107560
Uniprot IDs		A0A024R571 B2R5U3 Q9H4M9	Q7L804
PDB IDs		2JQ6 2KFF 2KFG 2KFH 2KSP	2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?
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