PRDX3 and RPS6KC1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		PRDX3	RPS6KC1
Description		peroxiredoxin 3	ribosomal protein S6 kinase C1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Early Endosome Cytosol Protein-containing Complex	Lysosome Endosome Early Endosome Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Thioredoxin Peroxidase Activity Alkyl Hydroperoxide Reductase Activity Kinase Binding Protein Kinase Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol Binding Protein Serine Kinase Activity
	Biological Process	Maternal Placenta Development Apoptotic Process Response To Oxidative Stress Mitochondrion Organization Positive Regulation Of Cell Population Proliferation Peptidyl-cysteine Oxidation Myeloid Cell Differentiation Response To Lipopolysaccharide Negative Regulation Of Kinase Activity Cellular Response To Oxidative Stress Cellular Response To Reactive Oxygen Species Response To Hydrogen Peroxide Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Redox Homeostasis Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Mitochondrial Membrane Potential Cellular Oxidant Detoxification	Protein Phosphorylation Signal Transduction
Pathways		Detoxification of Reactive Oxygen Species
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779)	Breast cancer in childhood cancer survivors ( 29059430) Breast cancer in childhood cancer survivors treated with less than 10 gray radiotherapy ( 29059430) Gut microbiota relative abundance (Ruminococcus belonging to family Erysipelotrichaceae) ( 33208821) Interleukin-6 levels in HIV infection ( 33095540) Refractive error ( 32231278)
Interacting Genes		15 interacting genes: CDC42 CUL4B FANCC GORASP2 HNRNPD MAGEA11 MAP3K13 NEK6 NR3C1 PRDX4 PTEN RPS6KC1 SUMO4 TNFRSF1A ZNF77	5 interacting genes: PBX2 PRDX3 SAAL1 SPHK1 VDR
Entrez ID		10935	26750
HPRD ID		05305	10204
Ensembl ID		ENSG00000165672	ENSG00000136643
Uniprot IDs		A0A384MTR2 P30048	A0A087X1U5 F5H7T0 F6RJM5 Q96S38
PDB IDs		5JCG 5UCX
Enriched GO Terms of Interacting Partners?
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