MORF4L1 and PLEKHA3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		MORF4L1	PLEKHA3
Description		mortality factor 4 like 1	pleckstrin homology domain containing A3
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleoplasm Sin3 Complex Nuclear Speck NuA4 Histone Acetyltransferase Complex	Golgi Membrane Golgi Apparatus Cytosol Membrane
	Molecular Function	Protein Binding Protein N-terminus Binding	Protein Binding Identical Protein Binding Phosphatidylinositol-4-phosphate Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transfer Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination Histone Acetylation Histone Deacetylation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation	Biological_process Ceramide Transport Intermembrane Lipid Transfer Ceramide 1-phosphate Transport
Pathways		HATs acetylate histones	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Coronary artery disease ( 32469254 30104761 33020668) Coronary heart disease ( 21378988) Lung adenocarcinoma ( 28604730) Lung cancer ( 31577861 28604730) Lung cancer in ever smokers ( 28604730) Myocardial infarction ( 33532862) Pulse pressure ( 27841878 30578418) Refractive error ( 32231278) Squamous cell lung carcinoma ( 28604730)	Alanine aminotransferase levels ( 33547301) Aspartate aminotransferase levels ( 33547301) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)
Interacting Genes		76 interacting genes: APP ARID3A ARRDC3 BEND7 BEX5 CALM1 CAMK2B CEP57L1 CWC27 DMAP1 DRAP1 DYSF EP300 FAM13C FAM9B FBXO16 FHL3 FXR2 GMCL1 GOLGA2 GOLGA6A GSC2 H3-4 HINFP HMBOX1 IKZF1 KPNA2 L3MBTL3 LHX2 LMNA LZTS2 MEOX1 MEOX2 MRFAP1 MRFAP1L1 MRGBP MRPL12 MSL1 NAB2 NAV2 NECAB1 NKD1 NMI PBXIP1 PHF12 PIBF1 PICK1 PLEKHA3 PSMC1 RACGAP1 RB1 RCBTB2 REL SH3GLB2 SYN3 TEPSIN TEX11 TFCP2 THAP1 TLE5 TNIP1 TNNT1 TNNT2 TRIM41 TULP3 UBP1 VPS26A ZBTB10 ZBTB26 ZBTB43 ZBTB8B ZBTB9 ZC3H7A ZNF276 ZNF438 ZNF449	9 interacting genes: DOK3 ERRFI1 MORF4L1 MRPL45 MYO15B PRKRA RNMT SH2B2 TCL1B
Entrez ID		10933	65977
HPRD ID		09532	09688
Ensembl ID		ENSG00000185787	ENSG00000116095
Uniprot IDs		Q9UBU8	Q9HB20
PDB IDs		2AQL 2EFI 2F5J 2F5K 2LKM 2N1D 6AGO 6INE	2KCJ 2MDX 3RCP
Enriched GO Terms of Interacting Partners?
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