CPSF4 and MIR19B1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
92

Data Source:
BioGRID (unspecified method)

		CPSF4	MIR19B1
Description		cleavage and polyadenylation specific factor 4	microRNA 19b-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex Intracellular Membrane-bounded Organelle	Extracellular Space Perinuclear Region Of Cytoplasm Blood Microparticle Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Sequence-specific Double-stranded DNA Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	Pre-mRNA Cleavage Required For Polyadenylation	Negative Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Interleukin-6 Production Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Cholesterol Homeostasis Negative Regulation Of Coagulation Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Cardiac Muscle Cell Proliferation Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Bacterial Lipopeptide Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Cholesterol Efflux Regulation Of Plasma Lipoprotein Particle Levels Negative Regulation Of Serine-type Endopeptidase Activity Regulation Of Canonical Wnt Signaling Pathway Involved In Cardiac Muscle Cell Fate Commitment Negative Regulation Of Reverse Cholesterol Transport Negative Regulation Of Matrix Metallopeptidase Secretion Positive Regulation Of Apoptotic Process Involved In Development Negative Regulation Of Apolipoprotein A-I-mediated Signaling Pathway
Pathways		Transport of Mature mRNA Derived from an Intronless Transcript Inhibition of Host mRNA Processing and RNA Silencing tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Diffuse cutaneous systemic sclerosis ( 29293537) Facial emotion recognition (sad faces) ( 28608620) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Serum metabolite levels ( 23093944) Tacrolimus trough concentration in kidney transplant patients ( 29160300)
Interacting Genes		10 interacting genes: CREBBP FIP1L1 MARK3 MEOX2 MID2 MIR19A MIR19B1 MIR92A2 MYOG SLC12A9	103 interacting genes: AIMP1 AIMP2 APOBEC3B AQR C1QBP CELF1 CELF2 CPSF1 CPSF2 CPSF3 CPSF4 CPSF6 CPSF7 CRTAP CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT21 P3H1 PATL1 PDCD11 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBBP6 RBFOX2 RBM12B RBM14 RBM4 RBMS2 RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 WDR33 WWP1 WWP2 YBX1 YBX2 YBX3 ZNF346 ZNF385A
Entrez ID		10898	406980
HPRD ID		04338
Ensembl ID		ENSG00000160917	ENSG00000284375
Uniprot IDs		B7Z7B0 O95639
PDB IDs		2D9N 2RHK 6DNH 6FBS 6FUW 6URG 6URO 7K95
Enriched GO Terms of Interacting Partners?
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