C1QL1 and NOTCH3

Number of citations of the paper that reports this interaction (PubMedID 25356737)
24

Data Source:
BioGRID (pull down)

		C1QL1	NOTCH3
Description		complement C1q like 1	notch receptor 3
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Collagen Trimer Cytoplasm Synaptic Cleft Climbing Fiber Presynapse	Golgi Membrane Extracellular Region Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Surface Actin Cytoskeleton Integral Component Of Membrane Receptor Complex
	Molecular Function	Molecular_function Signaling Receptor Binding Protein Binding	Calcium Ion Binding Protein Binding Signaling Receptor Activity Identical Protein Binding Cadherin Binding
	Biological Process	Locomotory Behavior Neuron Remodeling Motor Learning Maintenance Of Synapse Structure	Regulation Of Transcription, DNA-templated Notch Signaling Pathway Axon Guidance Regulation Of Developmental Process
Pathways			Pre-NOTCH Processing in the Endoplasmic Reticulum Pre-NOTCH Transcription and Translation Pre-NOTCH Processing in Golgi Pre-NOTCH Processing in Golgi Notch-HLH transcription pathway Defective LFNG causes SCDO3 NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH3 Activation and Transmission of Signal to the Nucleus NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription Noncanonical activation of NOTCH3
Drugs
Diseases
GWAS		Asthma ( 31619474) Blood protein levels ( 30072576) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Craniofacial microsomia ( 26853712) DNA methylation (variation) ( 23725790) Hip bone mineral density and total body fat mass (bivariate analysis) ( 32963334) White matter hyperintensity burden ( 25663218)	Pulse pressure ( 27841878 30578418) Toxoplasma gondii sag1 antibody levels ( 33204752)
Interacting Genes		2 interacting genes: IKZF3 NOTCH3	54 interacting genes: ANKRD28 BAG2 BTF3L4 C1QL1 C8orf76 CBFA2T2 CHUK CNTD1 CPNE6 CRIP2 CSNK2B DLL1 EGFL7 FBLN1 GGT6 HOXA1 JAG1 JAG2 KAT2B LINC00839 LTBP1 MAML1 MAML2 MAML3 MBD1 MPPED2 MTDH MYC NEDD9 NUFIP2 PPIA PRR20A PRR20B PRR20C PRR20D PRR20E PSEN1 PSEN2 RBPJ RET RMI2 SCGB3A1 SHANK3 SLC39A1 SNW1 SNX19 SORBS3 SPTLC2 TMEM108 TNNT2 TPT1 UPF1 WDR25 XKR8
Entrez ID		10882	4854
HPRD ID		12712	02607
Ensembl ID		ENSG00000131094	ENSG00000074181
Uniprot IDs		O75973	Q9UM47
PDB IDs			4ZLP 5CZV 5CZX
Enriched GO Terms of Interacting Partners?
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