FTCD and PALS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FTCD	PALS1
Description		formimidoyltransferase cyclodeaminase	protein associated with LIN7 1, MAGUK p55 family member
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Centriole Cytosol Plasma Membrane Smooth Endoplasmic Reticulum Membrane Extracellular Exosome	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Plasma Membrane Adherens Junction Bicellular Tight Junction Apical Plasma Membrane Axon Protein-containing Complex Myelin Sheath Adaxonal Region Perikaryon Lateral Loop Schmidt-Lanterman Incisure Extracellular Exosome
	Molecular Function	Protein Binding Folic Acid Binding Microtubule Binding Glutamate Formimidoyltransferase Activity Formimidoyltetrahydrofolate Cyclodeaminase Activity	Protein Binding ATP Binding Protein Domain Specific Binding
	Biological Process	Folic Acid-containing Compound Metabolic Process Cytoskeleton Organization Histidine Catabolic Process To Glutamate And Formamide Histidine Catabolic Process To Glutamate And Formate Tetrahydrofolate Interconversion	Morphogenesis Of An Epithelial Sheet Gene Expression Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Central Nervous System Neuron Development Cerebral Cortex Development Peripheral Nervous System Myelin Maintenance Myelin Assembly Protein Localization To Myelin Sheath Abaxonal Region Protein Localization To Plasma Membrane
Pathways		Histidine catabolism	Tight junction interactions
Drugs		Tetrahydrofolic acid Glutamic acid (6R)-Folinic acid
Diseases
GWAS		Blood protein levels ( 30072576) Mastocytosis ( 32752121) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: CCDC183 HDAC2 HGS KASH5 MED4 PALS1	17 interacting genes: ARF6 BHLHB9 CRB3 DLGAP4 FTCD LIN7A LIN7B LIN7C MPP4 NEK9 NUMB PARD6B PATJ SNTG2 SOCS4 SRGAP2B TRAF2
Entrez ID		10841	64398
HPRD ID		08430	09508
Ensembl ID		ENSG00000160282	ENSG00000072415
Uniprot IDs		O95954	Q658X5 Q8N3R9
PDB IDs			1Y76 3UIT 4UU5 4UU6 4WSI
Enriched GO Terms of Interacting Partners?
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