FAXDC2 and PGRMC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAXDC2	PGRMC2
Description		fatty acid hydroxylase domain containing 2	progesterone receptor membrane component 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nuclear Envelope Endoplasmic Reticulum Endomembrane System Membrane Integral Component Of Membrane
	Molecular Function	C-4 Methylsterol Oxidase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity	Steroid Hormone Receptor Activity Steroid Binding Protein Binding Heme Transmembrane Transporter Activity Heme Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Sterol Biosynthetic Process Positive Regulation Of Megakaryocyte Differentiation	Heme Transport Steroid Hormone Mediated Signaling Pathway Adipose Tissue Development
Pathways			RHOA GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle
Drugs
Diseases
GWAS			Bone mineral density (total hip) ( 29883787)
Interacting Genes		34 interacting genes: AQP6 ARL13B CD79A CGRRF1 CLDN7 CREB3L1 CYB5R3 EBP ELOVL4 ERGIC3 FCER1G FFAR2 GOLT1A GPR152 GPX8 HSD17B13 LMNA MGST3 NEMP1 PANX1 PDGFRB PGRMC2 RETREG3 SLC10A1 SLC10A6 SLC30A8 STOM STX4 TMEM106C TMEM139 TMEM31 TMEM86B TMPRSS2 TMX2	57 interacting genes: AQP10 ART5 BAG4 C5 COX20 CYB561D2 CYP4F2 DGAT2L6 DHRSX EI24 FA2H FAXDC2 FXYD6 FXYD6-FXYD2 GET3 GHITM GPR151 ITGAM ITPRIP LPAR3 MALL MFHAS1 MFSD5 ORMDL1 PEDS1-UBE2V1 PEX16 PGRMC1 PLLP PMP22 RNF8 RUSF1 SFXN1 SLC16A13 SLC30A8 SLC38A1 SLC39A13 SLC9B2 SMPD2 ST6GAL2 STX3 TAS2R19 TECR TF TMEM107 TMEM187 TMEM19 TMEM208 TMEM60 TMEM86A TMEM86B TSPAN2 UBXN8 VAPA VEZT YIPF2 ZDHHC21 ZFPL1
Entrez ID		10826	10424
HPRD ID		12832	09665
Ensembl ID		ENSG00000170271	ENSG00000164040
Uniprot IDs		Q96IV6	O15173
PDB IDs
Enriched GO Terms of Interacting Partners?
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