SRSF10 and SRSF4

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid)

		SRSF10	SRSF4
Description		serine and arginine rich splicing factor 10	serine and arginine rich splicing factor 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck	Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	RNA Binding Protein Binding RS Domain Binding Unfolded Protein Binding	RNA Binding MRNA Binding Protein Binding Sequence-specific MRNA Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated MRNA Splice Site Selection Cytosolic Transport Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Response To Insulin Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways		mRNA Splicing - Major Pathway	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs			Artenimol
Diseases
GWAS		Chronotype ( 30696823) Obesity-related traits ( 23251661)	Carotid plaque maximum area ( 32469969) Hematocrit ( 32888494) Hemoglobin ( 32888494) Mean area of carotid plaque ( 32469969) Schizophrenia ( 26531332) Tourette syndrome ( 30818990)
Interacting Genes		18 interacting genes: CLK1 CLK3 CSNK2A1 DAPK1 FBXO7 FUS MPP1 PTPN11 RNPS1 SNRNP70 SREK1 SRSF1 SRSF4 SYCE1L TRA2A TRA2B YWHAB YWHAG	23 interacting genes: DYRK1A FUS GEMIN2 HAP1 HTATSF1 PNN PPARGC1A PRPF38A RNPS1 SART1 SCAF11 SMURF1 SMURF2 SREK1 SRPK1 SRRM2 SRSF10 SRSF2 SRSF6 TICAM1 TRA2B UBE2I ZDHHC17
Entrez ID		10772	6429
HPRD ID		05562	09052
Ensembl ID		ENSG00000188529	ENSG00000116350
Uniprot IDs		A0A0S2Z504 B3KNY6 O75494 Q5JRI1	Q08170
PDB IDs
Enriched GO Terms of Interacting Partners?
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