AHCYL1 and JOSD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		AHCYL1	JOSD2
Description		adenosylhomocysteinase like 1	Josephin domain containing 2
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Apical Plasma Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Extracellular Exosome	Cytosol
	Molecular Function	RNA Binding Adenosylhomocysteinase Activity Protein Binding Identical Protein Binding	Thiol-dependent Deubiquitinase Protein Binding
	Biological Process	MRNA Polyadenylation Protein Export From Nucleus One-carbon Metabolic Process Apoptotic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Anion Transport Response To Calcium Ion Mitochondrion-endoplasmic Reticulum Membrane Tethering	Protein Deubiquitination
Pathways		PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Josephin domain DUBs
Drugs
Diseases
GWAS		Height ( 31562340)
Interacting Genes		25 interacting genes: BID CDKN2C DACH1 GEM HBQ1 HEXIM2 HGS HSPA6 ITPR1 JOSD2 LRRK2 MEOX2 MFHAS1 PLEKHG5 PPL PRDM6 PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 SUMO2 UACA ZNF165	13 interacting genes: AHCYL1 CMTM5 COQ8A FKBP7 MDK PLA2G2A STUB1 SYP TRAPPC2 TRAPPC2B TTPA UBC YIF1A
Entrez ID		10768	126119
HPRD ID		07613	15297
Ensembl ID		ENSG00000168710	ENSG00000161677
Uniprot IDs		A0A024R0A8 O43865	A0A024R4G2 Q7Z7N5 Q8TAC2
PDB IDs		3MTG	6PGV
Enriched GO Terms of Interacting Partners?
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