GRAP and TOX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		GRAP	TOX
Description		GRB2 related adaptor protein	thymocyte selection associated high mobility group box
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Presynapse	Nucleus
	Molecular Function	Protein Binding	Protein Binding Chromatin DNA Binding
	Biological Process	Ras Protein Signal Transduction Cell-cell Signaling Sensory Perception Of Sound	Natural Killer Cell Differentiation CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment NK T Cell Lineage Commitment Leukocyte Differentiation Chromatin Organization Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Cerebral Cortex Neuron Differentiation Positive Regulation Of Natural Killer Cell Differentiation CD4-positive, Alpha-beta T Cell Lineage Commitment CD8-positive, Alpha-beta T Cell Lineage Commitment Lymph Node Development Peyer's Patch Development Positive Regulation Of DNA Demethylation Regulation Of Positive Thymic T Cell Selection Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Signaling by SCF-KIT
Drugs
Diseases
GWAS		Copper levels ( 26025379)	Chronotype ( 30696823) Cognitive performance ( 19734545) Height ( 31562340) High myopia ( 31816047) Hyperopia ( 25233373) Mercury levels ( 26025379) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Myopia ( 27182965 25233373) Oily fish consumption ( 32066663) Parental longevity (father's attained age) ( 29227965) Pork consumption ( 32066663) Psychological resilience (outcome-based) ( 31081985) Refractive astigmatism ( 25367360) Refractive error ( 23396134 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Superior temporal sulcus banks volume ( 31530798) Systolic blood pressure ( 30224653) Type 1 diabetes ( 34012112) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		19 interacting genes: ARHGAP32 DPPA4 EPOR FASLG FYN GAB2 KHDRBS1 KIT LAT LCK PLCG1 PRRG4 RAI1 RBPMS REL SHC1 SOS1 TOX TRIM21	6 interacting genes: BANP DMRTB1 GRAP KRTAP12-1 KRTAP26-1 ZDHHC17
Entrez ID		10750	9760
HPRD ID		05062	12113
Ensembl ID		ENSG00000154016	ENSG00000198846
Uniprot IDs		I3L2P9 Q13588	O94900
PDB IDs
Enriched GO Terms of Interacting Partners?
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