PNMA2 and THAP7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PNMA2	THAP7
Description		PNMA family member 2	THAP domain containing 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleolus	Nucleus Nucleoplasm Chromosome Nuclear Speck Nuclear Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Transcription Corepressor Binding DNA Binding Protein Binding Nucleosomal Histone Binding Methylated Histone Binding Identical Protein Binding Histone Deacetylase Binding Metal Ion Binding Protein N-terminus Binding Lysine-acetylated Histone Binding C2H2 Zinc Finger Domain Binding Phosphorylated Histone Binding General Transcription Initiation Factor Binding
	Biological Process	Positive Regulation Of Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Histone Acetylation Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Brain morphology (MOSTest) ( 32665545) Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes		34 interacting genes: BYSL CBX8 CCDC33 CDC37 CNNM3 DDX21 ENKD1 FAM161A GPATCH2L HAPLN2 INO80B LRR1 LYN MISP MORF4L2 NTAQ1 PPIG PRPF31 PSMA1 RNF6 RNF8 RPL9 RTP5 SCNM1 SDCBP THAP7 TOP3B TTLL10 ZNF408 ZNF417 ZNF587 ZNF669 ZNF688 ZNF785	63 interacting genes: ANKRD28 APP CCDC136 CCDC85B CCNDBP1 CDC37 CYSRT1 DESI2 DVL3 EFEMP2 EHMT2 FBXO7 FHL3 FSD2 GABARAPL1 GNAI1 GOLGA2 GOLGA6L9 H3C1 H4C1 HCFC1 HDAC3 HOXA1 KRT27 KRT31 KRT34 KRT40 KRTAP1-3 KRTAP10-3 KRTAP10-8 KRTAP17-1 KRTAP4-12 LDOC1 LNX1 LURAP1 LZTS2 MAGOHB MAP1LC3B MCC MDFI MID2 MTUS2 NBPF19 NOTCH2NLA NTAQ1 PELI2 PHC2 PHF19 PICK1 PIN1 PNMA2 PPP3CC SET TAF1B TFIP11 THAP11 TLE5 TPM3 TRAF1 TRAF2 TRAF5 ZDHHC17 ZRANB1
Entrez ID		10687	80764
HPRD ID		04915	15500
Ensembl ID		ENSG00000240694	ENSG00000184436
Uniprot IDs		Q5U5Z3 Q9UL42	Q9BT49
PDB IDs
Enriched GO Terms of Interacting Partners?
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