SMC2 and NCAPD2

Number of citations of the paper that reports this interaction (PubMedID 10958694)
45

Data Source:
HPRD (in vivo)

		SMC2	NCAPD2
Description		structural maintenance of chromosomes 2	non-SMC condensin I complex subunit D2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Chromatin Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome	Nuclear Chromosome Condensed Chromosome, Centromeric Region Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Chromatin Binding Single-stranded DNA Binding Protein Binding ATP Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization	Mitotic Chromosome Condensation Meiotic Chromosome Condensation Cell Division
Pathways		Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes	Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Basal cell carcinoma ( 31174203 33549134) HDL cholesterol levels ( 32203549) Keratinocyte cancer (MTAG) ( 31174203) Oily fish consumption ( 32066663) Orofacial clefts (maternal alcohol consumption interaction) ( 21618603) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042) Pork consumption ( 32066663) Sensorimotor dexterity ( 31596458)
Interacting Genes		12 interacting genes: ABCC5 CDC42 DISC1 DNMT3B ERP44 GULP1 LIG4 NCAPD2 PTEN SMC4 SUMO2 TRAF3IP1	8 interacting genes: CDC42 CDK1 CNN1 CSNK2A1 ERC1 SMC2 SMC4 SUMO2
Entrez ID		10592	9918
HPRD ID		09277	06472
Ensembl ID		ENSG00000136824	ENSG00000010292
Uniprot IDs		A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1	B3KMS0 B3KY03 Q15021
PDB IDs		4U4P
Enriched GO Terms of Interacting Partners?
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