CCT2 and ERLIN2

Number of citations of the paper that reports this interaction (PubMedID 23190606)
8

Data Source:
BioGRID (pull down)

		CCT2	ERLIN2
Description		chaperonin containing TCP1 subunit 2	ER lipid raft associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Zona Pellucida Receptor Complex Extracellular Region Cytosol Chaperonin-containing T-complex Microtubule Azurophil Granule Lumen Cell Body Extracellular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Membrane Protein-containing Complex Membrane Raft
	Molecular Function	Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding	Protein Binding Cholesterol Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Chaperone Mediated Protein Folding Independent Of Cofactor Chaperone-mediated Protein Complex Assembly Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	Cholesterol Metabolic Process Ubiquitin-dependent ERAD Pathway SREBP Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Fatty Acid Biosynthetic Process
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Neutrophil degranulation Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle	ABC-family proteins mediated transport Signaling by FGFR1 in disease Defective CFTR causes cystic fibrosis Signaling by plasma membrane FGFR1 fusions
Drugs
Diseases
GWAS		Height ( 18391951) Logical memory (delayed recall) in normal cognition ( 29274321) Urinary albumin excretion ( 30220432) Urinary albumin excretion (no hypertensive medication) ( 30220432) Urinary albumin-to-creatinine ratio ( 31630189 31511532)	Axial length ( 24144296)
Interacting Genes		25 interacting genes: ACTA1 ACTB CCT4 EEF2 ERLIN2 ESR1 FCHSD2 GLI1 HSP90AB1 HSP90B1 LINC01554 NPSR1 OGT PRPF40A PSMC6 PSMD2 PTEN RPS3 SUMO2 SUMO4 TUBA1B VAV2 VRK2 YWHAG ZNRD2	1 interacting genes: CCT2
Entrez ID		10576	11160
HPRD ID		06895	15437
Ensembl ID		ENSG00000166226	ENSG00000147475
Uniprot IDs		P78371 V9HW96	A0A384ME54 O94905
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8 7LUM 7LUP
Enriched GO Terms of Interacting Partners?
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