ARFGEF2 and SLC9A8

		ARFGEF2	SLC9A8
Description		ADP ribosylation factor guanine nucleotide exchange factor 2	solute carrier family 9 member A8
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Cytosol Axonemal Microtubule Membrane Cytoplasmic Vesicle Asymmetric Synapse Symmetric Synapse Dendritic Spine Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome	Golgi Membrane Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Kinase A Regulatory Subunit Binding GABA Receptor Binding	Protein Binding Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity
	Biological Process	Receptor Recycling Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Endomembrane System Organization Protein Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Intracellular Signal Transduction Regulation Of Catalytic Activity	Ion Transport Sodium Ion Transmembrane Transport Regulation Of Intracellular PH Potassium Ion Transmembrane Transport Anion Transmembrane Transport Proton Transmembrane Transport
Pathways		Association of TriC/CCT with target proteins during biosynthesis	Sodium/Proton exchangers
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anger ( 24489884) Birth weight ( 31043758) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Offspring birth weight ( 31043758) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 34021172)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Coronary artery disease ( 29212778) Early cardiac repolarization ( 31600170) Gut microbiota (beta diversity) ( 27723756) Multiple sclerosis ( 24076602) Psoriasis ( 20953189)
Interacting Genes		11 interacting genes: ARFGEF1 EXOC7 GABRB1 GABRB2 GABRB3 PNPLA2 PRKAR1A PRKAR2A PRPF40A PTGIS SLC9A8	4 interacting genes: ARFGEF2 MEOX2 MOCS3 TMSB4XP6
Entrez ID		10564	23315
HPRD ID		09250	18062
Ensembl ID		ENSG00000124198	ENSG00000197818
Uniprot IDs		Q59FR3 Q86TH5 Q9Y6D5	B4DIX7 Q9Y2E8
PDB IDs		3L8N 3SWV
Enriched GO Terms of Interacting Partners?
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