NEBL and XIRP1

Number of citations of the paper that reports this interaction (PubMedID 23985323)
17

Data Source:
BioGRID (two hybrid, pull down, unspecified method, protein complementation assay)

		NEBL	XIRP1
Description		nebulette	xin actin binding repeat containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Stress Fiber Z Disc I Band Extracellular Exosome	Stress Fiber Focal Adhesion
	Molecular Function	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding	RNA Binding Protein Binding Actin Filament Binding
	Biological Process	Cardiac Muscle Thin Filament Assembly	Actin Filament Organization Negative Regulation Of Protein Binding
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Atrial fibrillation ( 28416822) Coronary artery aneurysm in Kawasaki disease ( 27171184) Gastroesophageal reflux disease ( 34187846) Heel bone mineral density ( 30598549) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Photic sneeze reflex ( 27182965) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Plasma anti-thyroid peroxidase levels ( 29678681) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Sporadic pituitary adenoma ( 26029870) Triglyceride levels x SSRI defined daily dose interaction in schizophrenia or bipolar disorder ( 33824429) Urate levels in lean individuals ( 25811787) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference ( 28552196) Walking pace ( 33128006)	Apolipoprotein A1 levels ( 32203549) Cognitive decline rate in late mild cognitive impairment ( 26252872) Daytime sleep phenotypes ( 27126917) Social communication problems ( 24564958)
Interacting Genes		37 interacting genes: ACAP1 ACTB ACTN1 ACTN3 CACNB2 CCDC125 CCDC136 CEP70 FAM9B GMCL1 GOLGA2 GOLGA6A HOMER3 KIFC3 LZTS2 MAD1L1 MIPOL1 MYPN NRP1 NUTM1 PIBF1 PIK3R3 PRKAB2 PRRG4 QARS1 SPAG5 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 VCL XIRP1 XIRP2 ZDHHC17 ZGPAT ZYX	9 interacting genes: ACTA1 ENAH EVL FLNC NEB NEBL SH3RF1 TRANK1 VASP
Entrez ID		10529	165904
HPRD ID		10403	16727
Ensembl ID		ENSG00000078114	ENSG00000168334
Uniprot IDs		O76041 Q59FZ8	Q702N8
PDB IDs		4F14
Enriched GO Terms of Interacting Partners?
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