IPO7 and H1-0

Number of citations of the paper that reports this interaction (PubMedID 10228156)
92

Data Source:
HPRD (in vitro)

		IPO7	H1-0
Description		importin 7	H1.0 linker histone
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Membrane	Chromatin Nucleosome Euchromatin Nucleus Nucleoplasm Golgi Apparatus Actin Cytoskeleton Nuclear Body Transcription Repressor Complex
	Molecular Function	Transporter Activity Protein Binding GTPase Regulator Activity Small GTPase Binding Histone Binding SMAD Binding	Minor Groove Of Adenine-thymine-rich DNA Binding Double-stranded DNA Binding RNA Binding Protein Binding Chromatin DNA Binding Nucleosomal DNA Binding
	Biological Process	Protein Import Into Nucleus Signal Transduction Innate Immune Response Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity	Negative Regulation Of Transcription By RNA Polymerase II Nucleosome Assembly Gene Silencing Nucleosome Positioning Chromosome Condensation Negative Regulation Of DNA Recombination Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways			Apoptosis induced DNA fragmentation Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS		Interleukin-10 levels ( 22205395)
Interacting Genes		11 interacting genes: AKTIP H1-0 KPNB1 LIMS1 LINC01554 PTEN RAN RPL23A RPL5 RPS7 SRP19	21 interacting genes: APP CCNE1 CDK1 CDK2 CDK4 CDK5 FBXO7 GRB2 HPF1 IKBKG IPO5 IPO7 KPNA2 KPNB1 NEDD4L NOA1 PARP1 PARP2 PRKCB RAD51B XBP1
Entrez ID		10527	3005
HPRD ID		09280	00819
Ensembl ID		ENSG00000205339	ENSG00000189060
Uniprot IDs		B3KNG9 O95373	P07305
PDB IDs			6HQ1 6LA2 6LA8 6LA9 6LAB 6N88 6N89 7DBP 7K5X
Enriched GO Terms of Interacting Partners?
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