SYNCRIP and SYT11

Number of citations of the paper that reports this interaction (PubMedID 10734137)
30

Data Source:
HPRD (in vitro)

		SYNCRIP	SYT11
Description		synaptotagmin binding cytoplasmic RNA interacting protein	synaptotagmin 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum Membrane CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex GAIT Complex Ribonucleoprotein Complex	Phagocytic Cup Lysosome Lysosomal Membrane Trans-Golgi Network Plasma Membrane Synaptic Vesicle Postsynaptic Density Axon Dendrite Clathrin-coated Vesicle Membrane Vesicle Early Phagosome Neuron Projection Terminal Bouton Dendritic Spine Perikaryon Synapse Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Recycling Endosome Recycling Endosome Membrane Excitatory Synapse Inhibitory Synapse Exocytic Vesicle Schaffer Collateral - CA1 Synapse Presynapse Integral Component Of Presynaptic Active Zone Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding MRNA 5'-UTR Binding	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Clathrin Binding Translation Initiation Factor Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Beta-tubulin Binding
	Biological Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Negative Regulation Of Translation CRD-mediated MRNA Stabilization Cellular Response To Interferon-gamma	Plasma Membrane Repair Negative Regulation Of Cytokine Production Vesicle Fusion Autophagy Learning Memory Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium-ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Dopamine Secretion Negative Regulation Of Endocytosis Negative Regulation Of Neurotransmitter Secretion Negative Regulation Of Phagocytosis Establishment Of Vesicle Localization Cellular Response To Calcium Ion Negative Regulation Of Clathrin-dependent Endocytosis Negative Regulation Of Synaptic Vesicle Endocytosis Regulation Of Defense Response To Bacterium Negative Regulation Of Microglial Cell Activation Negative Regulation Of Membrane Invagination Regulation Of Phagosome Maturation Positive Regulation Of Protein Localization To Phagocytic Vesicle Negative Regulation Of Clathrin-coated Pit Assembly Calcium Ion Regulated Lysosome Exocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Parkinson's disease ( 21292315 25064009) Serum cancer antigen 15.3 levels ( 31666285) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		110 interacting genes: A1CF APOBEC1 APP CIP2A CSDE1 EPRS1 ESR1 GRB2 HABP4 HMGA1 HMGA2 HNRNPAB HNRNPD HNRNPK IL7R INSR IVNS1ABP KLHL3 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYPOP NUPR1 OGT PABPC1 PCSK7 PLCG1 PRMT8 PTPN11 SMN1 SUMO2 SYT1 SYT11 SYT2 SYT3 SYT4 SYT7 SYT8 SYT9 TRIM55 TRIM63	7 interacting genes: APPBP2 GPR35 PLEKHO1 PRKN SGTA SGTB SYNCRIP
Entrez ID		10492	23208
HPRD ID		06734	12289
Ensembl ID		ENSG00000135316	ENSG00000132718
Uniprot IDs		A0A7I2V309 A0A7I2YQN2 B7Z645 O60506 Q59GL1	Q9BT88
PDB IDs		2DGU 2MXT 2NBB 6KOR
Enriched GO Terms of Interacting Partners?
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