TRIM38 and EIF1B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		TRIM38	EIF1B
Description		tripartite motif containing 38	eukaryotic translation initiation factor 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleoplasm Cytoplasm Cytosol	Cellular_component Eukaryotic 43S Preinitiation Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Protein Kinase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	RNA Binding Translation Initiation Factor Activity Protein Binding Ribosomal Small Subunit Binding
	Biological Process	Protein Polyubiquitination Regulation Of Gene Expression Positive Regulation Of Autophagy Protein Ubiquitination Regulation Of Protein Localization Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Positive Regulation Of Transcription, DNA-templated Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity	Translational Initiation Regulation Of Translational Initiation
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Cardiac hypertrophy ( 21348951) Fish- and plant-related diet ( 32066663) Height ( 28552196) Iron status biomarkers ( 19084217) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)	Refractive error ( 32231278)
Interacting Genes		34 interacting genes: ATXN1 BYSL EIF1B GMCL1 GORASP2 HSPA1A HSPA1B HSPA1L HSPA2 HSPA8 MTMR6 MTURN PIAS4 PSMA4 RFC5 RIPK1 RNF4 SDCBP SOX2 SPTLC1 STXBP1 TCEA2 TSBP1 TSPYL4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2U ZNF764	6 interacting genes: ATXN1 DVL2 DVL3 PEX19 SPG21 TRIM38
Entrez ID		10475	10289
HPRD ID		15555	17032
Ensembl ID		ENSG00000112343	ENSG00000114784
Uniprot IDs		A0A024QZY4 O00635	O60739 Q6FG85
PDB IDs
Enriched GO Terms of Interacting Partners?
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