ACAA2 and PKD1L1

		ACAA2	PKD1L1
Description		acetyl-CoA acyltransferase 2	polycystin 1 like 1, transient receptor potential channel interacting
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Cilium Membrane Calcium Channel Complex Ciliary Membrane Non-motile Cilium
	Molecular Function	RNA Binding Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA Hydrolase Activity Acetyl-CoA C-acyltransferase Activity Protein Binding Palmitoyl-CoA Hydrolase Activity Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity	Calcium Channel Activity Protein Binding
	Biological Process	Fatty Acid Beta-oxidation Cholesterol Biosynthetic Process Cellular Response To Hypoxia Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process	Detection Of Nodal Flow Detection Of Mechanical Stimulus Calcium Ion Transmembrane Transport Left/right Axis Specification Cell-cell Adhesion
Pathways		Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Acute anterior uveitis in ankylosing spondylitis ( 32492107) Apolipoprotein A1 levels ( 29084231) Cerebrospinal fluid immune biomarker levels ( 32066700) Cholesterol ester levels in very large HDL ( 29084231) Free cholesterol levels in medium HDL ( 29084231) HDL cholesterol ( 18193044) HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heschl's gyrus morphology ( 25130324) Large HDL particle concentration ( 29084231) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Mean diameter of HDL particles ( 29084231) Medium HDL particle concentration ( 29084231) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231) Refractive error ( 32231278) Response to selective serotonin reuptake inhibitors in depression ( 27622933) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Total cholesterol levels in HDL ( 29084231) Total cholesterol levels in large HDL ( 29084231)	Anxiety disorder ( 25390645) Diastolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Gut microbiota alpha diversity (Shannon index) ( 33208821) Hepatitis C induced liver fibrosis ( 22841784) Obstructive sleep apnea during REM sleep (apnea hypopnea index) ( 29077507) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		6 interacting genes: APP HSPB2 LAMTOR5 PKD1L1 SCP2 TERT	11 interacting genes: ABCA13 ABCC3 ACAA2 C7orf57 CLK1 LINC02902 MGAT2 PKD1L1-AS1 PLCB2 PSME3 RPL6
Entrez ID		10449	168507
HPRD ID		10380	10154
Ensembl ID		ENSG00000167315	ENSG00000158683
Uniprot IDs		B3KNP8 P42765	Q8TDX9
PDB IDs		4C2J 4C2K
Enriched GO Terms of Interacting Partners?
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