MYL9 and CDC42BPA

Number of citations of the paper that reports this interaction (PubMedID 11283256)
26

Data Source:
HPRD (in vitro)

		MYL9	CDC42BPA
Description		myosin light chain 9	CDC42 binding protein kinase alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Cytosol Muscle Myosin Complex Cell Cortex Z Disc	Cytoplasm Cytosol Cytoskeleton Cell-cell Junction Lamellipodium Cell Leading Edge Actomyosin Extracellular Exosome
	Molecular Function	Calcium Ion Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Identical Protein Binding Protein Serine Kinase Activity
	Biological Process	Regulation Of Muscle Contraction Platelet Aggregation	Protein Phosphorylation Cell Migration Peptidyl-threonine Phosphorylation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Intracellular Signal Transduction
Pathways		EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle
Drugs
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825) Blood urea nitrogen levels ( 31152163) Cardiovascular death or myocardial infarction in response to clopidogrel treatment ( 32472697) Diastolic blood pressure ( 28135244) Low density lipoprotein cholesterol levels ( 33339817) Macular thickness ( 30535121) Mercury levels ( 26025379) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494) Optic cup area ( 25631615 31798171) Optic disc area ( 25631615 31798171 28073927) Optic disc size ( 31809533) SAPHO syndrome ( 33816493) Smoking initiation ( 33082346) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference adjusted for body mass index ( 34021172) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: CDC42BPA CEP250 HSPB1 LRRK2 MSGN1 MYH9 PPP1R16B SLC12A5 TXN2	10 interacting genes: CDC42 CDC42BPB LIMK1 LIMK2 MYL2 MYL9 PPM1A PPP1R12C SNAPIN TAF1
Entrez ID		10398	8476
HPRD ID		17619	04562
Ensembl ID		ENSG00000101335	ENSG00000143776
Uniprot IDs		A0A384NY64 P24844	Q5VT25
PDB IDs
Enriched GO Terms of Interacting Partners?
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