LAMC3 and CWC25

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		LAMC3	CWC25
Description		laminin subunit gamma 3	CWC25 spliceosome associated protein homolog
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Basement Membrane Membrane Extracellular Matrix	Nucleus Nucleoplasm U2-type Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 1 Spliceosome
	Molecular Function	Structural Molecule Activity	Protein Binding
	Biological Process	Visual Perception Animal Organ Morphogenesis Tissue Development Astrocyte Development Cell Migration Substrate Adhesion-dependent Cell Spreading Retina Development In Camera-type Eye	MRNA Splicing, Via Spliceosome
Pathways		Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)	Intraocular pressure ( 29617998)
Interacting Genes		20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160	8 interacting genes: CCDC85B FMR1 GSDMB KRT34 LAMC3 MDM2 OGT TRIM21
Entrez ID		10319	54883
HPRD ID		05069	07892
Ensembl ID		ENSG00000050555	ENSG00000273559
Uniprot IDs		Q8N2D6 Q9Y6N6	Q9NXE8
PDB IDs			5YZG 6ZYM
Enriched GO Terms of Interacting Partners?
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