CDKN2A and NAT2

  • Number of citations of the paper that reports this interaction (PubMedID 25640309)
  • 8
  • Data Source:
  • BioGRID (two hybrid)

CDKN2A

NAT2

Description cyclin dependent kinase inhibitor 2A N-acetyltransferase 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Bladder cancer ( 24163127 20972438)
  • Blood metabolite levels ( 24816252)
  • Blood metabolite ratios ( 24816252)
  • Cholesterol, total ( 24097068 20686565)
  • Coronary artery disease ( 29212778 33020668)
  • Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223)
  • Insulin resistance/response ( 25798622)
  • Iron status biomarkers (total iron binding capacity) ( 33536631)
  • Iron status biomarkers (transferrin levels) ( 25352340)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver enzyme levels (alkaline phosphatase) ( 33972514)
  • Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
  • Liver injury in anti-tuberculosis drug treatment ( 31109976)
  • Medication use (calcium channel blockers) ( 31015401)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolic syndrome ( 31589552)
  • Metabolic traits ( 21886157)
  • Metabolite levels ( 23823483)
  • Myocardial infarction ( 33532862)
  • Night sleep phenotypes ( 27126917)
  • Paclitaxel-induced neuropathy ( 23776197)
  • Serum metabolite levels ( 33031748)
  • Total cholesterol levels ( 28334899 33339817)
  • Triglyceride levels ( 32203549 28334899 29403010 33339817 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 24097068 20686565)
  • Urinary metabolite levels in chronic kidney disease ( 31959995)
  • Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995)
  • Urinary metabolites ( 26352407 21572414)
  • Urinary metabolites (H-NMR features) ( 24586186)
  • Youthful appearance (self-reported) ( 32339537)
Interacting Genes 172 interacting genes: - ACLY ACTB ACTG1 ACTN4 AHNAK AKT1 ALDOB ANAPC15 ANGPTL4 ANKRA2 ANKRD12 AOPEP ARFIP2 ARNT ASPRV1 AZIN1 BAAT BCL2L1 BECN1 CA9 CARF CASC3 CCDC180 CCDC183 CCND2 CCNDBP1 CCNE1 CCNG1 CD44 CDC14B CDC42 CDC45 CDC5L CDC6 CDC7 CDK4 CDK6 CDKN2AIP CDKN2B CDKN2C CENPA CRELD2 CTBP2 CTSV CYLC2 DEAF1 DNAI1 E2F1 E4F1 EEF2 EFHC2 EGR1 EPHA2 EPHA3 EXOC2 FGFR4 FN1 FRAT2 GALNT12 GAPDH GGA1 GGA3 GLIPR2 GLIS1 GLIS2 GMNN GSPT1 H2BU1 HGF HIF1A HLA-DOB HNRNPA2B1 HNRNPC HNRNPU HRAS HSP90AA1 HSP90AB1 HSPA4 HSPA8 HUWE1 ISOC2 KAT5 LATS2 MAF1 MAP2K1 MAP2K5 MAP3K5 MAPK10 MAPK14 MAPK3 MAPK8 MCM10 MCM2 MCM5 MCM6 MDM2 MDM4 MMRN1 MTR MYC MYL12A NAT2 NCL NFX1 NMI NOP53 NPM1 NSD3 ORC4 PCNA PDCD6 PDGFRA PEX19 PPP1R9B PRKCA PSMC3 PTP4A3 RAF1 RASA1 RASSF1 RBM26 RIN2 RPL11 RPS7 RUVBL2 SEC61B SERTAD1 SFRP4 SIT1 SIVA1 SIX2 SLC4A1 SMARCA4 SNRPA SNRPB SOX3 SOX4 STK11 TBRG1 TDRD7 TEAD2 TERT TFDP1 TGFB1 TMEFF1 TMOD1 TP53 TP63 TPI1 TRIM28 TRIP12 TSC1 TUBA1A TUBA1C TUBB TUBB4B UBE2A UBE4B UBL7 USP26 VAMP1 VHL WRN YY1 ZFP91 ZGRF1 ZNF227 ZNF410 ZNF420 ZNF687 ZUP1 18 interacting genes: APC APP AURKA BAG4 CDKN2A CDKN2C CLU ERBB2 FZR1 HMMR IGF1R MBD4 NAA10 NBN PALB2 PPM1D STK11 WT1
Entrez ID 1029 10
HPRD ID 02542 02000
Ensembl ID ENSG00000147889 ENSG00000156006
Uniprot IDs K7PML8 P42771 Q8N726 A4Z6T7 P11245
PDB IDs 1A5E 1BI7 1DC2 2A5E 2PFR
Enriched GO Terms of Interacting Partners?
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