STAG1 and CLDN18

		STAG1	CLDN18
Description		stromal antigen 1	claudin 18
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Chromatin Nucleus Nucleoplasm Chromosome Cytosol Cohesin Complex Nuclear Matrix Nuclear Body Mitotic Spindle Pole	Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane
	Molecular Function	Chromatin Binding Protein Binding	Structural Molecule Activity Protein Binding Identical Protein Binding
	Biological Process	Sister Chromatid Cohesion Cell Division Mitotic Spindle Assembly	Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Response To Ethanol Negative Regulation Of Bone Resorption Digestive Tract Development Bicellular Tight Junction Assembly TNFSF11-mediated Signaling Pathway Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Osteoclast Development
Pathways		Meiotic synapsis Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion SUMOylation of DNA damage response and repair proteins Estrogen-dependent gene expression	Tight junction interactions
Drugs
Diseases
GWAS		Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Apolipoprotein B levels ( 32203549) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 28892062 25673413) Body shape index ( 34021172) C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Central corneal thickness ( 32528159 31798171 29760442) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 29212778 30104761) Dentures ( 31235808) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 30275531) Height ( 25282103) Intraocular pressure ( 29617998) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Low density lipoprotein cholesterol levels ( 32154731) Multisite chronic pain ( 33830993 31194737) Myocardial infarction ( 33532862) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Plateletcrit ( 32888494) Schizophrenia ( 28991256 25056061 29483656 30285260) Waist circumference adjusted for body mass index ( 34021172)	Alzheimer's disease in APOE e4- carriers ( 25778476) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: ASPH CALM1 CEP63 CLDN18 GUK1 MSL2 RAD21 SMAD2 SMAD9 SMC1B STAG2 VDR WFDC5	3 interacting genes: EHHADH PMP22 STAG1
Entrez ID		10274	51208
HPRD ID		05076	13066
Ensembl ID		ENSG00000118007	ENSG00000066405
Uniprot IDs		Q4LE48 Q8WVM7	P56856
PDB IDs		5QSM 5QSN 5QSO 5QSP 5QSQ 5QSR 5QSS 5QST 5QSU 5QSV 5QSW 5QSX 5QSY 5QSZ 6QB5 6R7O 6RRC 6RRK 6WG3
Enriched GO Terms of Interacting Partners?
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