RAMP3 and HSPB3

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RAMP3	HSPB3
Description		receptor activity modifying protein 3	heat shock protein family B (small) member 3
Image
GO Annotations	Cellular Component	Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex	Nucleus Cytoplasm Nuclear Speck
	Molecular Function	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity
	Biological Process	Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane Adrenomedullin Receptor Signaling Pathway	Response To Unfolded Protein
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Pramlintide
Diseases
GWAS		Hepatic lipid content in extreme obesity ( 25246029)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Systolic blood pressure (dietary potassium intake interaction) ( 29212900)
Interacting Genes		15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1	19 interacting genes: ANP32A BBOX1 HSPB2 HSPB8 LRIF1 LSM14B MED31 MED8 MRPL38 NSMF OLFML3 PRPF4B RAMP3 RBM48 RTL8A SETDB1 TCAP UNC119 ZZEF1
Entrez ID		10268	8988
HPRD ID		05517	06861
Ensembl ID		ENSG00000122679	ENSG00000169271
Uniprot IDs		A4D2L1 O60896	Q12988 Q6ICS9
PDB IDs		6UUS 6UVA	6F2R
Enriched GO Terms of Interacting Partners?
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