RIDA and SPEN

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		RIDA	SPEN
Description		reactive intermediate imine deaminase A homolog	spen family transcriptional repressor
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Matrix Peroxisome Cytosol Extracellular Exosome	Nucleus Nucleoplasm Transcription Repressor Complex Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Endoribonuclease Activity, Producing 3'-phosphomonoesters Deaminase Activity Long-chain Fatty Acid Binding Identical Protein Binding Transition Metal Ion Binding 2-iminobutanoate Deaminase Activity 2-iminopropanoate Deaminase Activity	DNA Binding Transcription Corepressor Activity RNA Binding MRNA Binding Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Kidney Development MRNA Catabolic Process Brain Development Negative Regulation Of Translation L-threonine Catabolic Process To Glycine Lung Development Response To Lipid Negative Regulation Of Epithelial Cell Proliferation MRNA Destabilization G1 To G0 Transition RNA Phosphodiester Bond Hydrolysis, Endonucleolytic Organonitrogen Compound Catabolic Process Response To Salt	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Neurogenesis
Pathways		Threonine catabolism	RHOBTB1 GTPase cycle
Drugs
Diseases
GWAS			Erectile dysfunction ( 30583798) Heel bone mineral density ( 28869591) Hemoglobin levels ( 32327693)
Interacting Genes		10 interacting genes: BANP DEAF1 HIVEP1 HPD MDM2 MT-CO2 SERPINA5 SPEN TMEM176A TRIB3	22 interacting genes: ATXN1 CLK1 CTBP1 DLX5 HDAC1 HDAC2 MBD3 MSX2 MTA2 NCOR1 NCOR2 PPARD RARA RBBP4 RBPJ RIDA RUNX1 RUNX1T1 SERTAD1 SOX9 SRPK2 UBE2L6
Entrez ID		10247	23013
HPRD ID		03924	10230
Ensembl ID		ENSG00000132541	ENSG00000065526
Uniprot IDs		A0A024R9H2 P52758	Q96T58
PDB IDs		1ONI	1OW1 2RT5 4P6Q
Enriched GO Terms of Interacting Partners?
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