KLRG1 and KLRC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		KLRG1	KLRC1
Description		killer cell lectin like receptor G1	killer cell lectin like receptor C1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex
	Molecular Function	Protein Binding Carbohydrate Binding Signaling Receptor Activity	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding HLA-E Specific Inhibitory MHC Class Ib Receptor Activity Protein Antigen Binding
	Biological Process	Inflammatory Response Cellular Defense Response Cell Surface Receptor Signaling Pathway Innate Immune Response	Negative Regulation Of T Cell Mediated Cytotoxicity Adaptive Immune Response CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Natural Killer Cell Inhibitory Signaling Pathway Cell Surface Receptor Signaling Pathway Innate Immune Response Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Refractive error ( 32231278) SjÃ¶gren's syndrome ( 28076899) Type 1 diabetes ( 34012112)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Blood protein levels ( 28240269) Granulocyte percentage of myeloid white cells ( 27863252) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Reticulocyte count ( 32888494)
Interacting Genes		8 interacting genes: ARL13B GPR42 GPX8 KLRC1 LEPROTL1 MRM1 RHOA SYNE4	46 interacting genes: ATP6V0B ATP6V0C BMP10 BRICD5 C3orf52 CD151 CD82 CGRRF1 CLDN11 CLEC2D CLEC7A CLRN2 CTXN3 CXCL14 CYB561A3 EMP1 EMP3 ERMP1 GJB2 GJB4 GJB6 GPR61 HLA-E KLRD1 KLRG1 LSMEM2 MAL MALL MS4A13 NKG7 PLP1 PMP22 PTPN11 PTPN6 SFTPC SUZ12 TMEM182 TMEM262 TMEM54 TMPPE TSPO2 UNC93B1 UPK1B VAMP5 VTI1B ZFPL1
Entrez ID		10219	3821
HPRD ID		16076	01192
Ensembl ID		ENSG00000139187	ENSG00000134545
Uniprot IDs		Q96E93	P26715
PDB IDs		3FF7	2RMX 2YU7 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?
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