Description |
cyclin dependent kinase 6 |
AKT serine/threonine kinase 1 |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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- ATP
- Arsenic trioxide
- Genistein
- Inositol 1,3,4,5-Tetrakisphosphate
- Resveratrol
- Archexin
- Enzastaurin
- Perifosine
- N-[2-(5-methyl-4H-1,2,4-triazol-3-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
- 5-(5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine
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Diseases |
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GWAS |
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Interacting Genes |
148 interacting genes:
ABI2
ACHE
AKT1
ANKRD12
APOBEC1
AR
ARAF
ARHGEF6
ARNT
ATF6B
ATXN1
BCL11A
BECN1
CASC3
CBLC
CBY1
CCND1
CCND2
CCND3
CCNE1
CCNH
CCNI
CD44
CDC37
CDC6
CDK14
CDK4
CDK7
CDKN1A
CDKN2A
CDKN2B
CDKN2C
CDKN2D
CLASRP
CNOT7
CTNNA1
CTNNB1
DDIT3
DEDD2
EBF4
EIF4ENIF1
ELK1
ELOA2
EPHA2
ERBB2
EZH2
FGFR4
FOXM1
FOXO3
FZR1
GLIS1
GLIS2
GOLGA4
GRM1
H1-1
HGF
HIF1A
HPD
HSF1
ISL1
KAT2A
KDELR2
KEAP1
KIF26B
KLF10
KRIT1
LATS2
LPIN1
MAP2K3
MAP2K5
MAP3K5
MAPK14
MCM10
MCM2
MEF2D
MET
MLLT3
MSL3
MYC
MZF1
N4BP1
NF2
NFATC3
NIPBL
NUMA1
OTP
PCNA
PDGFRA
PML
POGZ
PPARGC1A
PPHLN1
PPM1B
PPP2CA
PRX
PSMA3
RAF1
RASSF1
RB1
RBL1
RBL2
RBM23
RBPMS
RGS3
RUNX1
SENP3
SGCE
SIRT1
SLBP
SNIP1
SORBS1
SOX10
SOX5
SRSF1
SRSF11
SRSF12
SRSF2
SRSF7
SSBP2
STK11
SUMO1
SYNPO2
TAC1
TAL2
TEAD2
TERT
TFDP1
TGFBR1
TJP2
TNFRSF1A
TP53
TPX2
TRA2A
TRA2B
TRAK1
TRIM15
TSC1
UHRF2
USP17L2
USP51
VGLL4
ZEB1
ZFP36
ZMYM3
ZNF101
ZNF174
ZNF335
ZSCAN1
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325 interacting genes:
ACAP1
ACAT2
ADCY10
AGAP2
AGR3
AHNAK
AHSA1
AKT1S1
AKT2
AKTIP
ALYREF
APLP2
APOC1
APOH
APP
APPL1
AR
ARAF
ARFIP2
ARNT
ATXN1
AURKA
BABAM1
BAD
BCL10
BCL2L1
BCL2L11
BCL3
BECN1
BEX1
BLVRA
BPGM
BRAF
BRCA1
BUB1
CAMKK1
CARHSP1
CASC3
CASP3
CASP9
CBLC
CCDC88A
CCND2
CCNE1
CCNF
CCNI
CD44
CDC37
CDC42
CDH1
CDK4
CDK6
CDKN1A
CDKN1B
CDKN1C
CDKN2A
CDKN2B
CDKN2C
CEP57L1
CEP76
CHEK1
CHUK
CLASP2
CLIP3
CLK2
CNOT9
CREB1
CREBBP
CSNK2A1
CTDSP2
CTNNA1
CTNNB1
CYLD
DAB2IP
DCTN1
DDIT4L
DLC1
DNAJB1
DNMT1
EEF1G
EIF4EBP1
EMSY
ENO2
EP300
EPHA2
EPSTI1
ERBB2
ESR1
ESR2
EZH2
FAF1
FANCA
FANCI
FASN
FBXO31
FBXW7
FGFR4
FOXO1
FOXO3
FOXO4
FUS
GAB2
GATA1
GATA2
GET4
GFAP
GJA1
GLIS2
GRB10
GRIN2A
GSK3A
GSK3B
H2BC21
H2BC3
HIF1A
HMOX1
HSP90AA1
HSP90AB1
HSPB1
HTT
IKBKB
IL13RA2
IL24
ILK
IMPDH2
IRAK1
IRS1
ITGB3
ITPR1
ITPR3
ITSN1
IWS1
JADE1
KANK1
KAT2A
KAT2B
KAT6A
KDELR2
KLHL3
KMT2D
KRT10
LANCL2
LATS2
LRRK2
LTB4R2
MAP2K3
MAP2K4
MAP2K5
MAP2K6
MAP3K11
MAP3K5
MAP3K8
MAPK14
MAPK8
MAPK8IP1
MAPK9
MAPKAP1
MAPKAPK2
MAPT
MATK
MDM2
MDM4
MESD
METTL1
MIS12
MLH3
MRC2
MS4A2
MSH2
MST1R
MTA3
MTCP1
MTOR
MTUS2
MUL1
MXD1
MYC
NCF2
NCOA4
NCOR2
NEDD4
NF1
NF2
NGB
NLGN3
NOL4
NOS3
NOTCH1
NR4A1
NRAS
NSD3
OSGIN1
PAK1
PCK1
PDE3A
PDE3B
PDGFRA
PDHB
PDK1
PDK2
PDPK1
PEA15
PFKFB1
PFKFB2
PFKP
PHB2
PI4K2B
PIAS1
PIAS2
PICK1
PIK3CA
PIK3R1
PIP5K1C
PKN2
PLCG1
PLEKHO1
PLP1
PLXNA1
PMS2
PPARGC1B
PPL
PPM1A
PPP2CA
PPP2R1A
PRG2
PRKCQ
PRKCZ
PRKDC
PSMC5
PTEN
PTGDS
PTPA
PTPN1
PTPN11
PTPN3
PYGO2
RAB3D
RAC1
RAF1
RARA
RASL10B
RASSF1
RGCC
RHEBL1
RNF11
RNF115
RPS6KB1
S100A14
S1PR1
SERPINB5
SETDB1
SH2B2
SH3RF1
SIRPA
SIRT1
SIRT6
SKI
SKP2
SLC9A3R1
SMAD2
SMAD3
SMAD4
SMAD7
SMARCB1
SMARCC1
SNCA
SNCB
SORBS2
SOX4
SP1
SP3
SRC
SRPK2
SRR
SSH1
ST14
STAT1
STK11
STK3
STK4
SULT4A1
SUPT6H
SYTL1
TBC1D4
TBC1D7
TCL1A
TCL1B
TCL6
TEAD2
TERF2IP
TERT
TFF1
THEM4
THRSP
TLR2
TMCC2
TNFRSF1A
TNFSF11
TNK2
TOPBP1
TP53
TRIB3
TRIM13
TRMT2B
TSC1
TSC2
TTC3
UBE2S
UCHL1
USP4
UXS1
VEGFA
VHL
VIM
WNK1
WNK4
XAF1
XIAP
YAP1
YBX1
YWHAZ
ZFP36L1
ZHX1
ZNF691
ZRANB1
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Entrez ID |
1021 |
207 |
HPRD ID |
04533 |
01261 |
Ensembl ID |
ENSG00000105810
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ENSG00000142208
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Uniprot IDs |
Q00534
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B0LPE5
B3KVH4
P31749
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PDB IDs |
1BI7
1BI8
1BLX
1G3N
1JOW
1XO2
2EUF
2F2C
3NUP
3NUX
4AUA
4EZ5
4TTH
5L2I
5L2S
5L2T
6OQL
6OQO
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1H10
1UNP
1UNQ
1UNR
2UVM
2UZR
2UZS
3CQU
3CQW
3MV5
3MVH
3O96
3OCB
3OW4
3QKK
3QKL
3QKM
4EJN
4EKK
4EKL
4GV1
5KCV
6BUU
6CCY
6HHF
6HHG
6HHH
6HHI
6HHJ
6NPZ
6S9W
6S9X
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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