MPHOSPH9 and KNTC1

		MPHOSPH9	KNTC1
Description		M-phase phosphoprotein 9	kinetochore associated 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Centriole Membrane	Spindle Pole Nucleus Cytoplasm Kinetochore Microtubule Cytosol Plasma Membrane Actin Cytoskeleton RZZ Complex
	Molecular Function		Protein Binding Small GTPase Binding
	Biological Process		Mitotic Sister Chromatid Segregation Mitotic Spindle Assembly Checkpoint Signaling Regulation Of Exit From Mitosis Cell Division Protein-containing Complex Assembly Protein Localization To Kinetochore Involved In Kinetochore Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Multiple sclerosis ( 19525953) Plasma anti-thyroglobulin levels ( 29678681) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 24509480 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Venous thromboembolism ( 31420334) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Adult body size ( 32376654) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 28892062) Body shape index ( 34021172) Hand grip strength ( 29691431) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin concentration ( 32888494) Menopause (age at onset) ( 26414677) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Walking pace ( 33128006)
Interacting Genes		18 interacting genes: ACACA ALPP ANXA11 ARF5 ATP6V0A2 CABP1 GSK3A HCAR3 KNTC1 MLEC MRPL19 RAB35 SNRNP35 SRSF9 SVIL TRA2A YWHAG YWHAZ	3 interacting genes: MPHOSPH9 PIAS4 ZWILCH
Entrez ID		10198	9735
HPRD ID		12022	09561
Ensembl ID		ENSG00000051825	ENSG00000184445
Uniprot IDs		Q99550	P50748
PDB IDs
Enriched GO Terms of Interacting Partners?
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