TSHZ1 and CD226

		TSHZ1	CD226
Description		teashirt zinc finger homeobox 1	CD226 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Raft
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Metal Ion Binding	Integrin Binding Protein Binding Protein Kinase Binding Cell Adhesion Molecule Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Middle Ear Morphogenesis Soft Palate Development	Cytokine Production Positive Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immunoglobulin Mediated Immune Response Cell Adhesion Signal Transduction Cell Recognition Positive Regulation Of Interferon-gamma Production Positive Regulation Of Mast Cell Activation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Chronotype ( 30696823) Colorectal or endometrial cancer ( 26621817) Motion sickness ( 25628336) Prostate cancer ( 29892016) Systolic blood pressure ( 30224653 30578418)	Autoimmune thyroid disease ( 32581359) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic widespread musculoskeletal pain ( 33331911) Eosinophil counts ( 32888494) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean platelet volume ( 22139419 19820697 31194788 32888494 27863252) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Primary sclerosing cholangitis ( 23603763 27992413) Reticulocyte fraction of red cells ( 32888494) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 33272962) Type 1 diabetes ( 21829393 25751624 17554260) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: APBB1 CD226	8 interacting genes: CNDP2 DOK6 FYN GALR1 ITGB2 NECTIN2 PVR TSHZ1
Entrez ID		10194	10666
HPRD ID		15308	09252
Ensembl ID		ENSG00000179981	ENSG00000150637
Uniprot IDs		A7YF73 Q6ZSZ6	J3QR77 Q15762
PDB IDs			6ISB 6O3O
Enriched GO Terms of Interacting Partners?
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