ARL4C and GIGYF2

		ARL4C	GIGYF2
Description		ADP ribosylation factor like GTPase 4C	GRB10 interacting GYF protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Filopodium	Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoplasmic Stress Granule Membrane Integral Component Of Membrane Vesicle Protein-containing Complex Perikaryon Proximal Dendrite
	Molecular Function	GTPase Activity Protein Binding GTP Binding Alpha-tubulin Binding	RNA Binding Protein Binding Cadherin Binding Proline-rich Region Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport Endocytic Recycling	Feeding Behavior Adult Locomotory Behavior Post-embryonic Development Posttranscriptional Gene Silencing Negative Regulation Of Translation Spinal Cord Motor Neuron Differentiation Mitotic G1 DNA Damage Checkpoint Signaling Multicellular Organism Growth Cellular Protein Metabolic Process Insulin-like Growth Factor Receptor Signaling Pathway Homeostasis Of Number Of Cells Within A Tissue Musculoskeletal Movement Neuromuscular Process Controlling Balance MRNA Destabilization
Pathways		NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Blood pressure measurement (high sodium and potassium intervention) ( 24165912) Central corneal thickness ( 29760442) Cognitive decline (age-related) ( 28078323) Initial pursuit acceleration in psychotic disorders ( 29064472) Pancreatic cancer ( 20686608) Systolic blood pressure x educational attainment (some college) interaction (2df) ( 32372009) Triglyceride levels ( 30108155)	Anxiety and stress-related disorders ( 31116379) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Coronary artery disease ( 32469254 29212778 33020668) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Hip circumference adjusted for BMI ( 34021172) Myocardial infarction ( 33532862) Schizophrenia ( 25056061 29483656 23974872)
Interacting Genes		3 interacting genes: APP GIGYF2 UBQLN4	14 interacting genes: APC ARL4C ATG16L1 CAB39 CNOT9 EPHA2 GRB10 GRB14 GRB7 METTL21A NMUR1 RBM12 SNRPB WBP11
Entrez ID		10123	26058
HPRD ID		11988	11639
Ensembl ID		ENSG00000188042	ENSG00000204120
Uniprot IDs		A0A024R4C5 P56559	Q6Y7W6
PDB IDs			5NVL 5NVM
Enriched GO Terms of Interacting Partners?
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