TSPAN1 and NFKBIB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		TSPAN1	NFKBIB
Description		tetraspanin 1	NFKB inhibitor beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Membrane Cell Junction Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Cytosol
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding
	Biological Process	Protein Stabilization	Transcription, DNA-templated Signal Transduction Cytoplasmic Sequestering Of NF-kappaB Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide
Pathways			Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Liver enzyme levels (gamma-glutamyl transferase) ( 33972514)
Interacting Genes		5 interacting genes: KDM4A MDK NFKBIB TFAM TMEM80	43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52
Entrez ID		10103	4793
HPRD ID		18232	07260
Ensembl ID		ENSG00000117472	ENSG00000104825
Uniprot IDs		O60635	G5E9C2 Q15653
PDB IDs
Enriched GO Terms of Interacting Partners?
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