ARPC1B and PMPCB

		ARPC1B	PMPCB
Description		actin related protein 2/3 complex subunit 1B	peptidase, mitochondrial processing subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Arp2/3 Protein Complex Focal Adhesion Actin Cytoskeleton Tubulobulbar Complex Extracellular Exosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Actin Filament Binding	Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Response To Estradiol Arp2/3 Complex-mediated Actin Nucleation Response To Estrogen	Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation EPHB-mediated forward signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Mitochondrial protein import Processing of SMDT1
Drugs		N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide (2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS		Alcohol consumption ( 31358974) Facial emotion recognition (sad faces) ( 28608620) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum metabolite levels ( 23093944)	Diverticular disease ( 30177863)
Interacting Genes		12 interacting genes: ACTB ACTR2 APP ARPC2 ARPC4 ARPC5 AURKA KEAP1 PAK1 PMPCB SRPK2 WAS	10 interacting genes: AP4M1 ARPC1B FXN MARK3 NPSR1 PMPCA PTGER4 VGF ZNF3 ZNHIT1
Entrez ID		10095	9512
HPRD ID		10366	07539
Ensembl ID		ENSG00000130429	ENSG00000105819
Uniprot IDs		A4D275 O15143	B3KM34 O75439 Q96CP5
PDB IDs		6UHC 6YW6
Enriched GO Terms of Interacting Partners?
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