USH1C and QKI

Number of citations of the paper that reports this interaction (PubMedID 16713569)
337

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USH1C	QKI
Description		USH1 protein network component harmonin	QKI, KH domain containing RNA binding
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GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Stereocilia Ankle Link Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Brush Border Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Apical Part Of Cell Synapse	Nucleus Cytoplasm Synapse
	Molecular Function	Protein Binding Spectrin Binding Actin Filament Binding	RNA Binding MRNA Binding Protein Binding SH3 Domain Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Sensory Perception Of Sound Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Length Cellular Protein-containing Complex Assembly Inner Ear Morphogenesis Inner Ear Auditory Receptor Cell Differentiation Photoreceptor Cell Maintenance Retinal Cone Cell Development Sensory Perception Of Light Stimulus Equilibrioception Actin Filament Bundle Assembly Inner Ear Receptor Cell Stereocilium Organization Protein Localization To Microvillus Brush Border Assembly	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process Regulation Of MRNA Splicing, Via Spliceosome MRNA Transport
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea	Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Body mass index ( 26426971) Macular thickness ( 30535121) Night sleep phenotypes ( 27126917)	Cataracts ( 34127677) Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Fasting insulin ( 34059833) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)
Interacting Genes		13 interacting genes: ANKS4B CDH23 CTNNAL1 ENKD1 FBXO7 MIPOL1 MYO7A PCDHB12 PRKAA2 QKI RAC1 USH1G USHBP1	50 interacting genes: APP ATXN1 CARM1 CCND3 CDKN2D DAZ1 DAZ4 DEPP1 DMRTB1 FBXO7 FHL3 FUBP3 HCLS1 HNRNPH2 HNRNPK IL7R LSM3 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 NABP1 PCBP1 PCBP2 PCBP4 PIAS1 PRKAB2 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA TEX11 THAP1 TIAL1 TSG101 U2AF2 USH1C WDR77
Entrez ID		10083	9444
HPRD ID		09241	06691
Ensembl ID		ENSG00000006611	ENSG00000112531
Uniprot IDs		A0A0S2Z4U9 A0A0S2Z4V1 Q9Y6N9	Q8WY44 Q96PU8
PDB IDs		1X5N 2KBQ 2KBR 2KBS 2LSR 3K1R 5F3X 5MV8 5MV9 5XBF	4JVH
Enriched GO Terms of Interacting Partners?
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