ABCC9 and LDHA

Number of citations of the paper that reports this interaction (PubMedID 12145195)
44

Data Source:
HPRD (in vivo)

		ABCC9	LDHA
Description		ATP binding cassette subfamily C member 9	lactate dehydrogenase A
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Inward Rectifying Potassium Channel Membrane Sarcomere Potassium Ion-transporting ATPase Complex	Nucleus Cytosol Membrane Extracellular Exosome
	Molecular Function	Cation Channel Activity Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity Potassium Channel Regulator Activity ATPase-coupled Cation Transmembrane Transporter Activity Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Transmembrane Transporter Binding ABC-type Transporter Activity	L-lactate Dehydrogenase Activity Protein Binding Kinase Binding Identical Protein Binding Cadherin Binding NAD Binding
	Biological Process	Inorganic Anion Transport Response To ATP Defense Response To Virus Transmembrane Transport Cardiac Conduction Potassium Ion Transmembrane Transport Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Transport Across Blood-brain Barrier Potassium Ion Import Across Plasma Membrane	Response To Hypoxia Lactate Metabolic Process Glycolytic Process Response To Nutrient Response To Xenobiotic Stimulus Response To Glucose NAD Metabolic Process Response To Hydrogen Peroxide Positive Regulation Of Apoptotic Process Response To Estrogen Post-embryonic Animal Organ Development Response To CAMP
Pathways		ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	Pyruvate metabolism
Drugs		ATP Glyburide Nicorandil	NADH Etheno-NAD Nicotinamide Oxamic Acid Stiripentol Copper Artenimol
Diseases
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 27680694) Gout ( 22179738) Hippocampal sclerosis of aging ( 24770881) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653 30578418)	Amyloid A serum levels ( 21124955) Serum metabolite levels ( 33031748)
Interacting Genes		7 interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA SOX5 STX1A	20 interacting genes: ABCC9 ACD DUX4 DYNLL1 FGFR1 GSK3A HNRNPD HULC KCNJ11 LDHB MAPK10 NDRG1 PCNA POT1 PTPRF TERF1 TINF2 UPF2 XRN1 YWHAQ
Entrez ID		10060	3939
HPRD ID		03258	01025
Ensembl ID		ENSG00000069431	ENSG00000134333
Uniprot IDs		A0A024RAV7 O60706	P00338 V9HWB9
PDB IDs			1I10 4AJP 4JNK 4L4R 4L4S 4M49 4OJN 4OKN 4QO7 4QO8 4QSM 4QT0 4R68 4R69 4RLS 4ZVV 5IXS 5IXY 5W8H 5W8I 5W8J 5W8K 5W8L 5ZJD 5ZJE 5ZJF 6BAD 6BAG 6BAX 6BAZ 6BB0 6BB1 6BB2 6BB3 6MV8 6MVA 6Q0D 6Q13 6SBU 6SBV 6ZZR
Enriched GO Terms of Interacting Partners?
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