TROAP and DYRK1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, affinity chromatography technology)

		TROAP	DYRK1B
Description		trophinin associated protein	dual specificity tyrosine phosphorylation regulated kinase 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nucleoplasm Chromosome
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Cell Adhesion	Protein Phosphorylation Myoblast Fusion Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription, DNA-templated Protein Autophosphorylation Adipose Tissue Development
Pathways
Drugs			Fostamatinib
Diseases
GWAS			Macular thickness ( 30535121)
Interacting Genes		19 interacting genes: BANP BYSL C19orf54 DDN DYNLT1 DYRK1A DYRK1B GIGYF1 KRT31 KRT40 KRT8 NBPF19 NOTCH2NLA OIP5 SSC4D TP53BP2 TRAF2 TRIM23 TRO	12 interacting genes: DCAF7 GSC2 HDAC5 ID2 MAP2K3 MAPK1 MAPK14 MBP PAK1 PCBD1 RANBP9 TROAP
Entrez ID		10024	9149
HPRD ID		04849	05188
Ensembl ID		ENSG00000135451	ENSG00000105204
Uniprot IDs		F8W130 Q12815	A0A024R0I0 A0A024R0J6 A0A024R0M8 Q9Y463
PDB IDs
Enriched GO Terms of Interacting Partners?
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