TOMM6 and CERS4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOMM6	CERS4
Description		translocase of outer mitochondrial membrane 6	ceramide synthase 4
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding	DNA Binding Protein Binding N-acyltransferase Activity Sphingosine N-acyltransferase Activity
	Biological Process	Protein Transport	Sphingolipid Biosynthetic Process Ceramide Biosynthetic Process
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy	Sphingolipid de novo biosynthesis
Drugs
Diseases
GWAS		Hip circumference adjusted for BMI ( 34021172)	Macular telangiectasia type 2 ( 33654266) Mean reticulocyte volume ( 32888494) Metabolite levels ( 31628463) Red cell distribution width ( 32888494) Refractive error ( 32231278) Serum metabolite levels ( 33031748) Serum metabolite ratios in chronic kidney disease ( 29545352) Sphingolipid levels ( 26068415) Sphingomyelin levels ( 31551469) Thyroid stimulating hormone levels ( 30367059 32769997) Very long-chain saturated fatty acid levels (fatty acid 24:0) ( 25378659)
Interacting Genes		14 interacting genes: AQP6 C1orf159 CD68 CERS4 DNAH8 ERGIC3 FFAR3 GLP1R ODF4 SEC61A2 SLC10A1 SLC16A2 SLC18A2 TMEM14B	47 interacting genes: - C1QL4 CCL4L2 CLEC1A COL4A5 CTXN3 CXCL16 CYB5R3 EMD FATE1 FCER1G FXYD6 FXYD6-FXYD2 GPR151 IER3IP1 IGFBP5 ITGAM JAGN1 LHFPL5 MS4A1 NAT8 NEU1 PLP2 PNLIPRP1 PTPN9 SCAMP5 SCD SERF1A SERF1B SERP2 SLC13A4 SLC29A2 SLC35A1 SLC35F6 SLC7A1 SMIM11 STX7 STX8 TEX264 TMEM119 TMEM176A TMEM254 TMEM72 TOMM6 TSPO2 UPK1B VAMP2
Entrez ID		100188893	79603
HPRD ID		19464	13962
Ensembl ID		ENSG00000214736	ENSG00000090661
Uniprot IDs		Q96B49	Q53HF9 Q9HA82
PDB IDs		7CK6
Enriched GO Terms of Interacting Partners?
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