ZBTB33 and CBFA2T3

Number of citations of the paper that reports this interaction (PubMedID 23251453)
9

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ZBTB33	CBFA2T3
Description		zinc finger and BTB domain containing 33	CBFA2/RUNX1 partner transcriptional co-repressor 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane	Golgi Membrane Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Wnt Signaling Pathway Intracellular Signal Transduction Negative Regulation Of Transcription, DNA-templated	Response To Hypoxia Transcription, DNA-templated Negative Regulation Of Cell Population Proliferation Granulocyte Differentiation Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Aerobic Respiration
Pathways
Drugs
Diseases
GWAS			Annualised percent change of cerebrospinal fluid AB1-42 levels ( 31370031) Carotid intima media thickness ( 30510157) Carotid intima media thickness (mean) ( 31801372) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Hair color ( 26926045) Hemoglobin levels ( 32327693) Immature fraction of reticulocytes ( 32888494) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean platelet volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Red cell distribution width ( 32888494) Red vs. brown/black hair color ( 30531825) Social autistic-like traits ( 24133439) Vitiligo ( 27723757)
Interacting Genes		11 interacting genes: CBFA2T3 CTNND1 GSDMD GYS1 NCOR1 NUDT22 PLS3 SELENOS SUMO2 SUMO3 TRIML2	24 interacting genes: ARHGEF6 CBFA2T2 CHRM4 EPM2AIP1 GAS8 GATAD2A GMEB2 HDAC1 HDAC3 MATN2 NUP98 PIN1 PRKAR2A RTN4IP1 RUNX1 RUNX1T1 SEC24A TCF3 VPS37C ZBTB33 ZBTB38 ZBTB4 ZBTB47 ZNF652
Entrez ID		10009	863
HPRD ID		02269	04847
Ensembl ID		ENSG00000177485	ENSG00000129993
Uniprot IDs		Q86T24	O75081
PDB IDs		2LT7 3FKC 3M4T 3M8V 4F6M 4F6N 5VMU 5VMV 5VMW 5VMX 5VMY 5VMZ 6DF5 6DF8 6DF9 6DFA 6DFB 6DFC 6V8U
Enriched GO Terms of Interacting Partners?
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