SOCS5

Description		suppressor of cytokine signaling 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Phosphatidylinositol 3-kinase Complex
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Signal Transduction Protein Ubiquitination Cytokine-mediated Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Interleukin-6 Production Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of T-helper 1 Cell Differentiation Negative Regulation Of T-helper 2 Cell Differentiation Phosphatidylinositol Phosphate Biosynthetic Process Negative Regulation Of Inflammatory Response Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Monocyte Chemotactic Protein-1 Production Vascular Endothelial Cell Response To Fluid Shear Stress
Pathways		Interleukin-4 and Interleukin-13 signaling Neddylation
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Cerebrospinal P-tau181p levels ( 28247064) Chronotype ( 30696823) Current cigarettes per day in chronic obstructive pulmonary disease ( 21685187) Height ( 28552196 20881960) Offspring birth weight ( 31043758) Pulse pressure (alcohol consumption interaction) ( 24376456) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		12 interacting genes: APP CASP3 EGFR ERBB2 ERBB3 ERBB4 IL4R KIT MET PLCB2 TMBIM1 UBC
Entrez ID		9655
HPRD ID		06159
Ensembl ID		ENSG00000171150
Uniprot IDs		O75159
PDB IDs
Enriched GO Terms of Interacting Partners?
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