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APOL1

Description apolipoprotein L1
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Endoplasmic Reticulum Lumen
  • Intrinsic Component Of Membrane
  • Very-low-density Lipoprotein Particle
  • High-density Lipoprotein Particle
  • Blood Microparticle
Molecular Function
  • Chloride Channel Activity
  • Protein Binding
  • Lipid Binding
Biological Process
  • Lipid Transport
  • Cholesterol Metabolic Process
  • Lipoprotein Metabolic Process
  • Innate Immune Response
  • Cytolysis By Host Of Symbiont Cells
  • Chloride Transmembrane Transport
Pathways
  • Scavenging of heme from plasma
  • Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
  • Post-translational protein phosphorylation
Drugs
  • Zinc
  • Zinc acetate
  • Zinc chloride
  • Zinc sulfate, unspecified form
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Diabetic kidney disease ( 26305897)
  • End-stage kidney disease ( 31178898)
  • End-stage renal disease ( 29885931)
  • Glomerulosclerosis ( 20668430)
Interacting Genes 4 interacting genes: APOA1 CACNA1I CDC23 TRIM32
Entrez ID 8542
HPRD ID 04774
Ensembl ID ENSG00000100342
Uniprot IDs B1AH95 O14791 Q2KHQ6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025