PLA2G6

Description		phospholipase A2 group VI
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Cytosol Plasma Membrane Integral Component Of Membrane Pseudopodium Centriolar Satellite
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Lysophospholipase Activity Phospholipase A2 Activity Protein Binding Calmodulin Binding Palmitoyl-CoA Hydrolase Activity Hydrolase Activity Serine Hydrolase Activity Protein Kinase Binding Identical Protein Binding ATP-dependent Protein Binding Calcium-independent Phospholipase A2 Activity Phosphatidyl Phospholipase B Activity Myristoyl-CoA Hydrolase Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Chemotaxis Positive Regulation Of Cytosolic Calcium Ion Concentration Memory Urinary Bladder Smooth Muscle Contraction Antibacterial Humoral Response Cardiolipin Biosynthetic Process Phosphatidylcholine Catabolic Process Response To Endoplasmic Reticulum Stress Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cardiolipin Acyl-chain Remodeling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Vasodilation Positive Regulation Of Exocytosis Phosphatidylethanolamine Catabolic Process Platelet Activating Factor Metabolic Process Phosphatidic Acid Metabolic Process Negative Regulation Of Synaptic Transmission, Glutamatergic Maternal Process Involved In Female Pregnancy Positive Regulation Of Protein Kinase C Signaling Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Arachidonic Acid Secretion Regulation Of Store-operated Calcium Channel Activity Positive Regulation Of Ceramide Biosynthetic Process
Pathways		Acyl chain remodelling of PC Acyl chain remodeling of CL Acyl chain remodelling of PE Role of phospholipids in phagocytosis COPI-independent Golgi-to-ER retrograde traffic
Drugs		Quinacrine
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Body fat percentage ( 26833246) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Cutaneous nevi ( 21478494 19578365) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) Mammographic density (dense area) ( 25342443) Melanoma ( 21983787 28212542) Nevus count ( 30429480) Nevus count or cutaneous melanoma ( 32341527 30429480) Percent mammographic density ( 25342443) Platelet distribution width ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Triglyceride levels ( 32203549 28334899 32154731) Triglycerides ( 24097068 20686565)
Interacting Genes		12 interacting genes: CACNA1I CALM1 CCDC33 CEP76 MAT2B NUP93 RCBTB2 RUSC1 SERTAD2 TRIM50 USP54 ZBTB42
Entrez ID		8398
HPRD ID		04675
Ensembl ID		ENSG00000184381
Uniprot IDs		O60733
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?