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TIAL1

Description TIA1 cytotoxic granule associated RNA binding protein like 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Lysosome
  • Cytoplasmic Stress Granule
  • Ribonucleoprotein Complex
Molecular Function
  • DNA Binding
  • RNA Binding
  • MRNA 3'-UTR Binding
  • MRNA 3'-UTR AU-rich Region Binding
  • MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
  • Regulation Of Transcription By RNA Polymerase II
  • Apoptotic Process
  • Defense Response
  • Germ Cell Development
  • Positive Regulation Of Cell Population Proliferation
  • Negative Regulation Of Cell Population Proliferation
  • Posttranscriptional Gene Silencing
  • Stem Cell Division
  • Positive Regulation Of Hippo Signaling
  • Positive Regulation Of Gene Silencing By MiRNA
Pathways
  • FGFR2 alternative splicing
Drugs
Diseases
GWAS
  • Depressive symptoms (stressful life events interaction) ( 27529621)
  • Monocyte percentage of white cells ( 32888494)
  • Parkinson's disease ( 27182965)
  • Response to carboplatin and paclitaxel in ovarian cancer (MTT IC50) ( 27047539)
Interacting Genes 40 interacting genes: AKAP8L AOC1 BPIFA1 C10orf55 CAMK2A CELF4 CREBBP DAZAP2 FAM168A FAM168B FUBP1 GRINA INCA1 KLF1 KRTAP8-1 MAGED1 MAPK1 MAPK1IP1L MBNL2 MIR106A MIR106B MIR145 MIR199A1 MIR20A MIR29A MIR29C MIR34A MIR9-2 PRR13 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBPMS2 SMN1 SMN2 SNRPA VPS37C
Entrez ID 7073
HPRD ID 04563
Ensembl ID ENSG00000151923
Uniprot IDs Q01085 Q49AS9
PDB IDs 1X4G 2CQI 2DH7
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025