HSD17B12

Description		hydroxysteroid 17-beta dehydrogenase 12
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Fatty Acid Elongase Complex Integral Component Of Membrane Extracellular Matrix
	Molecular Function	Fibronectin Binding Protein Binding Collagen Binding Heparin Binding Oxidoreductase Activity Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity 17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity Long-chain-fatty-acyl-CoA Reductase Activity 17-beta-hydroxysteroid Dehydrogenase (NADP+) Activity 3-oxo-arachidoyl-CoA Reductase Activity 3-oxo-behenoyl-CoA Reductase Activity 3-oxo-lignoceroyl-CoA Reductase Activity 3-oxo-cerotoyl-CoA Reductase Activity
	Biological Process	Fatty Acid Biosynthetic Process Estrogen Biosynthetic Process Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Long-chain Fatty-acyl-CoA Biosynthetic Process
Pathways		Androgen biosynthesis Synthesis of very long-chain fatty acyl-CoAs
Drugs
Diseases
GWAS		Adult body size ( 32376654) Age at first birth ( 34211149) Age at first sexual intercourse ( 34211149) Birth length ( 25281659) Body mass index ( 26961502 25673413 29273807) Chronotype ( 30696823) Coronary artery disease ( 29212778 33020668) Essential hypertension (time to event) ( 32589924) FEV1 ( 30804560) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Lung function (forced vital capacity) ( 24929828) Lung function (FVC) ( 30804560) Morning person ( 30696823) Neuroblastoma ( 22941191) Neuroblastoma or malignant cutaneous melanoma ( 31605138) Sleep start time ( 33075057) Sporadic neuroblastoma ( 28545128) Type 2 diabetes ( 28566273 30297969) Waist circumference ( 28552196)
Interacting Genes		3 interacting genes: AMBRA1 UBQLN1 UBQLN2
Entrez ID		51144
HPRD ID		09989
Ensembl ID		ENSG00000149084
Uniprot IDs		Q53GQ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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