MUTYH

Description		mutY DNA glycosylase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	DNA Repair Base-excision Repair Mismatch Repair Depurination
Pathways
Drugs
Diseases
GWAS		Composite immunoglobulin trait (IgA/IgM) ( 28628107) Periventricular white matter hyperintensities ( 32517579)
Interacting Genes		20 interacting genes: AGTRAP APEX1 BAAT CYLC2 FANCC HRAS LMNA LRSAM1 MSANTD3 MSH6 PCNA RPA1 RPA4 SEC61B SIRT6 SMAD1 TDRD7 TNFRSF9 TSTD2 XPA
Entrez ID		4595
HPRD ID		05380
Ensembl ID		ENSG00000132781
Uniprot IDs		D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7
PDB IDs		1X51 3N5N
Enriched GO Terms of Interacting Partners?
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