CCDC88C

Description		coiled-coil domain containing 88C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cell Junction
	Molecular Function	G-protein Alpha-subunit Binding Guanyl-nucleotide Exchange Factor Activity Frizzled Binding Protein Binding Microtubule Binding PDZ Domain Binding Identical Protein Binding Protein Self-association Dynein Light Intermediate Chain Binding
	Biological Process	Regulation Of Protein Phosphorylation Apical Constriction Small GTPase Mediated Signal Transduction Cytoskeleton-dependent Intracellular Transport Stress-activated Protein Kinase Signaling Cascade Cytoplasmic Microtubule Organization Protein Destabilization Non-canonical Wnt Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Negative regulation of TCF-dependent signaling by DVL-interacting proteins
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683 23535729) Breast cancer, ovarian cancer or prostate cancer (pleiotropy) ( 27432226) Daytime sleep phenotypes ( 27126917) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) White matter hyperintensity volume ( 33293549) White matter hyperintensity volume (adjusted for hypertension) ( 33293549) White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes		8 interacting genes: APP DVL1 FBXO7 GNAI3 ITSN2 MAPK8 TAFAZZIN TSC22D1
Entrez ID		440193
HPRD ID		19136
Ensembl ID		ENSG00000015133
Uniprot IDs		B4DZB8 Q9P219
PDB IDs
Enriched GO Terms of Interacting Partners?
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