MPL

Description		MPL proto-oncogene, thrombopoietin receptor
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Cell Surface Integral Component Of Membrane Nuclear Membrane Neuron Projection Neuronal Cell Body
	Molecular Function	Protein Binding Thrombopoietin Receptor Activity
	Biological Process	Neutrophil Homeostasis Monocyte Homeostasis Thrombopoietin-mediated Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Platelet Aggregation Cellular Response To Hypoxia Positive Regulation Of Platelet Formation Eosinophil Homeostasis Basophil Homeostasis
Pathways		Platelet Aggregation (Plug Formation)
Drugs		Romiplostim SB-559448 Eltrombopag Thrombopoietin Avatrombopag Lusutrombopag
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		10 interacting genes: ANKRA2 ATXN2L IRS2 JAK2 PTPN11 PTPRF SHC1 SOCS1 THPO YWHAQ
Entrez ID		4352
HPRD ID		01161
Ensembl ID		ENSG00000117400
Uniprot IDs		P40238
PDB IDs
Enriched GO Terms of Interacting Partners?
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