KCNMA1

Description		potassium calcium-activated channel subfamily M alpha 1
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GO Annotations	Cellular Component	Plasma Membrane Caveola Voltage-gated Potassium Channel Complex Integral Component Of Membrane Apical Plasma Membrane Postsynaptic Membrane
	Molecular Function	Actin Binding Voltage-gated Potassium Channel Activity Protein Binding Calcium-activated Potassium Channel Activity Metal Ion Binding Large Conductance Calcium-activated Potassium Channel Activity
	Biological Process	Response To Hypoxia Potassium Ion Transport Response To Osmotic Stress Cellular Potassium Ion Homeostasis Response To Carbon Monoxide Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Volume Response To Calcium Ion Micturition Smooth Muscle Contraction Involved In Micturition Relaxation Of Vascular Associated Smooth Muscle Potassium Ion Transmembrane Transport
Pathways		Ca2+ activated K+ channels cGMP effects Sensory processing of sound by inner hair cells of the cochlea Acetylcholine inhibits contraction of outer hair cells
Drugs		Chlorzoxazone Bendroflumethiazide Procaine Hydroflumethiazide Hydrochlorothiazide Miconazole Diazoxide Halothane Dequalinium Trimebutine
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Bell's palsy ( 33602968) Blood pressure ( 24954895) Bone mineral density (spine) ( 26911590) Educational attainment ( 25201988) Estimated glomerular filtration rate ( 31152163 31015462) Glucocorticoid-induced osteonecrosis ( 26265699) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Heel bone mineral density ( 30598549 28869591) Hypospadias ( 25108383) Initial pursuit acceleration ( 29064472) Intraocular pressure ( 31959993) Lean body mass ( 28552196) Lumbar spine bone mineral density ( 29499414 22504420) Male-pattern baldness ( 28196072) Mortality in heart failure ( 20400778) Myopia ( 27182965) Obesity ( 21708048) Refractive error ( 32231278) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556) Schizophrenia ( 33169155) Smoking cessation in chronic obstructive pulmonary disease ( 29631575) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		7 interacting genes: CACNA1H GGT1 HMOX2 KCNMB1 MAP1A PTK2 SFTPD
Entrez ID		3778
HPRD ID		15967
Ensembl ID		ENSG00000156113
Uniprot IDs		A0A087WZL8 A0A1W2PP94 A0A1W2PPY5 A0A1W2PQK5 A0A1W2PQU4 A0A1W2PR56 A0A1W2PR62 A0A1W2PRN5 A0A1W2PSD3 B7ZMF5 D5MRH1 Q12791 Q59FH2 Q5SVJ7 S4R453
PDB IDs		2K44 3MT5 3NAF 6ND0 6V22 6V35 6V38 6V3G 6V5A
Enriched GO Terms of Interacting Partners?
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